N-(4-nitrophenyl)dimethylphosphinamide

Base Information

• Chemical Name: N-(4-nitrophenyl)dimethylphosphinamide
• CAS No.: 82720-46-5
• Molecular Formula: C8H11 N2 O3 P
• Molecular Weight: 214.16
• Mol file: 82720-46-5.mol

Synonyms:N-(4-nitrophenyl)dimethylphosphinamide

Chemical Property of N-(4-nitrophenyl)dimethylphosphinamide

Chemical Property:

• Vapor Pressure: 9.2E-05mmHg at 25°C
• Boiling Point: 339.4°C at 760 mmHg
• Flash Point: 159.1°C
• Density: 1.327g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-nitrophenyl)dimethylphosphinamide

There total 1 articles about N-(4-nitrophenyl)dimethylphosphinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

4-nitro-aniline (100-01-6,104810-17-5) + dimethylphosphinic acid chloride (1111-92-8) → N-(4-nitrophenyl)dimethylphosphinamide (82720-46-5)

Guidance literature:

With pyridine; In 1,2-dimethoxyethane; for 4h; Ambient temperature;

DOI:10.1021/jm00352a027

Reference yield:

N-(4-nitrophenyl)dimethylphosphinamide (82720-46-5) → C8H13N2OP (344295-53-0)

Guidance literature:

With hydrogenchloride; iron; In water; N,N-dimethyl-formamide; Heating;

DOI:10.1021/jm00352a027

Reference yield:

N-(4-nitrophenyl)dimethylphosphinamide (82720-46-5) → C21H20N3OP (82720-26-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Fe, conc. aq. HCl / dimethylformamide; H₂O / Heating

2: conc. aq. NH₃ / methanol / 0.17 h

With hydrogenchloride; ammonium hydroxide; iron; In methanol; water; N,N-dimethyl-formamide;

DOI:10.1021/jm00352a027

upstream raw materials:

4-nitro-aniline

dimethylphosphinic acid chloride

Downstream raw materials:

C₈H₁₃N₂OP

C₂₁H₂₀N₃OP

Refernces