methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside

Base Information

• Chemical Name: methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside
• CAS No.: 951011-25-9
• Molecular Formula: C₂₉H₂₉IO₅
• Molecular Weight: 584.451
• Mol file: 951011-25-9.mol

Synonyms:methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside

Chemical Property of methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside

There total 1 articles about methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside (161663-92-9) → methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside (951011-25-9)

Guidance literature:

With morpholine; iodine; In dichloromethane; benzene; at 50 ℃; for 3h;

DOI:10.1021/ol701480x

Reference yield: 53.0%

methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside (951011-25-9) + 1,3,4,6-tetra-O-acetyl-2-deoxy-D-glucopyranose (69515-91-9) → C41H46O12 (1013036-33-3)

Guidance literature:

With indium; In dichloromethane; for 48h; stereoselective reaction; Reflux;

DOI:10.1021/ol7029257

Reference yield:

methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-7-iodo-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside (951011-25-9) + D-glucal triacetate (2873-29-2) → methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-6,6,7,7-tetradehydro-7-(11,12-di-O-acetyl-9,10-dideoxy-D-erythro-hex-2-enopyranosyl)-α-D-glucoheptopyranoside + methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-6,6,7,7-tetradehydro-7-(11,12-di-O-acetyl-9,10-dideoxy-D-erythro-hex-2-enopyranosyl)-α-D-glucoheptopyranoside

Guidance literature:

indium; In dichloromethane; at 50 ℃; for 3h; Title compound not separated from byproducts.;

DOI:10.1021/ol701480x

upstream raw materials:

methyl-2,3,4-tri-O-benzyl-6,7-dideoxy-6,6,7,7-tetradehydro-α-D-glucoheptopyranoside

Downstream raw materials:

C₄₁H₄₆O₁₂