4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside

Base Information

• Chemical Name: 4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside
• CAS No.: 870543-36-5
• Molecular Formula: C₂₃H₂₈O₆
• Molecular Weight: 400.472
• Mol file: 870543-36-5.mol

Synonyms:4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside

Chemical Property of 4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside

There total 6 articles about 4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl bromide (100-39-0) + 4-methoxyphenyl 2,3-O-isopropylidene-α-L-rhamnopyranoside (583040-99-7) → 4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside (870543-36-5)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 25 ℃; for 12h;

DOI:10.1002/anie.200502615

Reference yield: 59.0%

benzyl bromide (100-39-0) + 4-methoxyphenyl 2,3-O-isopropylidene-α-L-rhamnopyranoside (583040-99-7) → 4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside (870543-36-5) + 4-methoxyphenyl 4-O-formyl-α-L-rhamnopyranoside

Guidance literature:

4-methoxyphenyl 2,3-O-isopropylidene-α-L-rhamnopyranoside; With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.666667h; Inert atmosphere;

benzyl bromide; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; Inert atmosphere;

Reference yield:

4-methoxyphenyl α-L-rhamnopyranoside (18918-36-0) → 4-methoxyphenyl 4-O-benzyl-2,3-O-isopropylidene-α-L-rhamnopyranoside (870543-36-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / 2,2-dimethoxypropane; BF₃*OEt₂ / 12 h / 0 - 25 °C

2: 100 percent / sodium hydride / dimethylformamide / 12 h / 0 - 25 °C

With boron trifluoride diethyl etherate; sodium hydride; 2,2-dimethoxy-propane; In N,N-dimethyl-formamide;

DOI:10.1002/anie.200502615

upstream raw materials:

benzyl bromide

4-methoxyphenyl 2,3-O-isopropylidene-α-L-rhamnopyranoside

4-methoxyphenyl α-L-rhamnopyranoside

4-methoxyphenyl 2,3,4-tetra-O-acetyl-α-L-rhamnopyranoside

Downstream raw materials:

4-methoxyphenyl 4-O-benzyl-α-L-rhamnopyranoside