ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

Base Information

Chemical Name:ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate
CAS No.:148549-35-3
Molecular Formula:C₂₆H₃₈O₂SSi₃
Molecular Weight:498.909
Hs Code.:

Synonyms:ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

Suppliers and Price of ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

There total 5 articles about ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 148549-32-0
ethyl 3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

: 882-33-7
diphenyldisulfane

: 148549-35-3
ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

Guidance literature:: With lithium diisopropyl amide;
DOI:10.1021/ja00062a089

Reference yield:

: 148549-30-8
2-bromo-5-(trimethylsilyl)-3-<(trimethylsilyl)ethynyl>pent-2-en-4-ynol

: 148549-35-3
ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / EtCO₂H / 30 h / Heating

2: 1.) LDA / 1.) THF, hexane, from -78 to -35 deg C, 1.5 h, 2.) THF, hexane, from -35 deg C to RT

3: 1.) LDA / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, RT, 16 h

With propionic acid; lithium diisopropyl amide;
DOI:10.1021/ja00099a020

Reference yield:

: 133968-81-7
1,1-dibromo-4-(trimethylsilyl)-2-[(trimethylsilyl)ethynyl]-1-buten-3-yne

: 148549-35-3
ethyl 2-(phenylthio)-3,3-bis<(trimethylsilyl)ethynyl>-5-(trimethylsilyl)pent-4-ynoate

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) n-BuLi / 1.) Et₂O, hexane, -95 deg C, 45 min, 2.) Et₂O, hexane

2: 93 percent / EtCO₂H / 30 h / Heating

3: 1.) LDA / 1.) THF, hexane, from -78 to -35 deg C, 1.5 h, 2.) THF, hexane, from -35 deg C to RT

4: 1.) LDA / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, RT, 16 h

With n-butyllithium; propionic acid; lithium diisopropyl amide;
DOI:10.1021/ja00099a020