1-(2-methoxyphenyl)-3,3-diphenylpropyne

Base Information

• Chemical Name: 1-(2-methoxyphenyl)-3,3-diphenylpropyne
• CAS No.: 164401-05-2
• Molecular Formula: C₂₂H₁₈O
• Molecular Weight: 298.384
• Mol file: 164401-05-2.mol

Synonyms:1-(2-methoxyphenyl)-3,3-diphenylpropyne

Chemical Property of 1-(2-methoxyphenyl)-3,3-diphenylpropyne

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-(2-methoxyphenyl)-3,3-diphenylpropyne

There total 6 articles about 1-(2-methoxyphenyl)-3,3-diphenylpropyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.6%

3-(2-methoxyphenyl)-1,1-diphenylprop-2-yn-1-ol (164401-06-3) → 1-(2-methoxyphenyl)-3,3-diphenylpropyne (164401-05-2)

Guidance literature:

With borane-THF; trifluoroacetic acid; at -10 - -5 ℃;

DOI:10.1007/BF02503791

Reference yield:

1-ethynyl-2-methoxybenzene (767-91-9) → 1-(2-methoxyphenyl)-3,3-diphenylpropyne (164401-05-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 40 percent / ethylmagnesium bromide / diethyl ether / 30 min, reflux, 12 h

2: 55.6 percent / BH₃*THF complex, trifluoroacetic acid / -10 - -5 °C

With borane-THF; ethylmagnesium bromide; trifluoroacetic acid; In diethyl ether;

DOI:10.1007/BF02503791

Reference yield:

benzophenone (119-61-9) → 1-(2-methoxyphenyl)-3,3-diphenylpropyne (164401-05-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 40 percent / ethylmagnesium bromide / diethyl ether / 30 min, reflux, 12 h

2: 55.6 percent / BH₃*THF complex, trifluoroacetic acid / -10 - -5 °C

With borane-THF; ethylmagnesium bromide; trifluoroacetic acid; In diethyl ether;

DOI:10.1007/BF02503791

upstream raw materials:

3-(2-methoxyphenyl)-1,1-diphenylprop-2-yn-1-ol

benzophenone

o-methoxystyrene

1-ethynyl-2-methoxybenzene