Technology Process of C22H40OSi2
There total 3 articles about C22H40OSi2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C15H34OSi2;
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sec.-butyllithium;
In
tetrahydrofuran; pentane;
at -78 ℃;
for 0.0833333h;
Inert atmosphere;
benzyl bromide;
In
tetrahydrofuran; pentane;
at -78 - 20 ℃;
for 4h;
Inert atmosphere;
DOI:10.1021/ol102352w
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
2.1: N,N,N,N,N,N-hexamethylphosphoric triamide; sec.-butyllithium / tetrahydrofuran; pentane / 0.08 h / -78 °C / Inert atmosphere
2.2: 4 h / -78 - 20 °C / Inert atmosphere
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sec.-butyllithium; triethylamine;
In
tetrahydrofuran; dichloromethane; pentane;
2.1: Retro-[1,4]-Brook rearrangement;
DOI:10.1016/j.tet.2012.06.005
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium bis(2-methoxyethoxy)aluminium dihydride / diethyl ether; toluene / 10 h / 0 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
3.1: N,N,N,N,N,N-hexamethylphosphoric triamide; sec.-butyllithium / tetrahydrofuran; pentane / 0.08 h / -78 °C / Inert atmosphere
3.2: 4 h / -78 - 20 °C / Inert atmosphere
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sec.-butyllithium; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride;
In
tetrahydrofuran; diethyl ether; dichloromethane; toluene; pentane;
3.1: Retro-[1,4]-Brook rearrangement;
DOI:10.1016/j.tet.2012.06.005
