1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid

Base Information

Chemical Name:1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid
CAS No.:81242-27-5
Molecular Formula:C12H14NO5S-
Molecular Weight:285.321
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80387149
Mol file:81242-27-5.mol

Synonyms:81242-27-5;1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid;202751-29-9;1-(4-methoxybenzenesulfonyl)pyrrolidine-2-carboxylic acid;1-[(4-methoxyphenyl)sulfonyl]pyrrolidine-2-carboxylic acid;1-(4-methoxyphenyl)sulfonylpyrrolidine-2-carboxylic acid;1-[(4-methoxyphenyl)sulfonyl]proline;1-((4-Methoxyphenyl)sulfonyl)pyrrolidine-2-carboxylic acid;CBMicro_042206;Cambridge id 6045607;Oprea1_479069;Oprea1_617726;SCHEMBL2705860;DTXSID80387149;LWZATQDWEXAGQR-UHFFFAOYSA-N;((4-methoxyphenyl)sulfonyl)proline;CIA75129;STL477639;AKOS000267396;AKOS016037527;1-(4-Methoxybenzene-1-sulfonyl)proline;BIM-0042036.P001;BB 0248085;CS-0302883;EN300-07167;SR-01000480156;1-[(4-methoxyphenyl)sulfonyl]-2-carboxypyrrolidine;SR-01000480156-1;Z45681501;1-(4-methoxyphenylsulfonyl)pyrrolidine-2-carboxylic acid;F0915-7765;1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxylic acid;1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2- carboxylic acid;1-[(4-METHOXYPHENYL)SULFONYL]PYRROLIDINE-2-CARBOXYLICACID;1-(4-methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid, AldrichCPR

Suppliers and Price of 1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-((4-Methoxyphenyl)sulfonyl)pyrrolidine-2-carboxylicacid 97%
5g
$ 701.00

American Custom Chemicals Corporation
1-(4-METHOXY-BENZENESULFONYL)-PYRROLIDINE-2-CARBOXYLIC ACID 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
1-(4-METHOXY-BENZENESULFONYL)-PYRROLIDINE-2-CARBOXYLIC ACID 95.00%
1G
$ 808.89

AK Scientific
1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylicacid
250mg
$ 554.00

AK Scientific
1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylicacid
100mg
$ 440.00

Total 7 raw suppliers

Chemical Property of 1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid

Chemical Property:

Vapor Pressure:1.74E-10mmHg at 25°C
Boiling Point:491.7°Cat760mmHg
PKA:3.39±0.20(Predicted)
Flash Point:251.2°C
PSA：92.29000
Density:1.403g/cm³
LogP:1.95160
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:285.06709375
Heavy Atom Count:19
Complexity:422

Purity/Quality:

97% ^*data from raw suppliers

1-((4-Methoxyphenyl)sulfonyl)pyrrolidine-2-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)S(=O)(=O)N2CCCC2C(=O)O

Technology Process of 1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid

There total 4 articles about 1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 81242-27-5
(S)-N-(p-methoxyphenylsulfonyl)proline

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 60 ℃;
DOI:10.1016/S0040-4020(01)00684-6

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 81242-27-5
1-(4-Methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 50 ℃; for 3h;
DOI:10.1021/ac00270a022

Reference yield:

: 1-Allyl-9-[(S)-1-(4-methoxy-benzenesulfonyl)-pyrrolidine-2-carbonyl]-1,9-dihydro-β-carboline-2-carboxylic acid 2,2,2-trichloro-ethyl ester

: 81242-27-5
(S)-N-(p-methoxyphenylsulfonyl)proline

: 316789-86-3
(S)-1-allyl-1,2-dihydro-2-(2,2,2-trichloroethoxycarbonyl)-β-carboline

: 255053-88-4
1-allyl-1,2-dihydro-2-(2,2,2-trichloroethoxycarbonyl)-β-carboline

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 0.5h; Title compound not separated from byproducts;
DOI:10.1016/S0040-4020(01)00684-6