N-[2-(trifluoromethyl)phenyl]methanesulfonamide

Base Information

Chemical Name:N-[2-(trifluoromethyl)phenyl]methanesulfonamide
CAS No.:50790-31-3
Molecular Formula:C₈H₈F₃NO₂S
Molecular Weight:239.218
Hs Code.:
DSSTox Substance ID:DTXSID501244094

Synonyms:N-[2-(trifluoromethyl)phenyl]methanesulfonamide;SCHEMBL16492688;GXPGKOGAGPTQOO-UHFFFAOYSA-N;DTXSID501244094;STL260614;AKOS003239123;50790-31-3;SR-01000478032;SR-01000478032-1

Suppliers and Price of N-[2-(trifluoromethyl)phenyl]methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-(trifluoromethyl)phenyl]methanesulfonamide

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:239.02278416
Heavy Atom Count:15
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CS(=O)(=O)NC1=CC=CC=C1C(F)(F)F

Technology Process of N-[2-(trifluoromethyl)phenyl]methanesulfonamide

There total 5 articles about N-[2-(trifluoromethyl)phenyl]methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.1%

: 124-63-0
methanesulfonyl chloride

: 88-17-5
2-(trifluoromethyl)benzenamine

: 50790-31-3
N‐(2‐(trifluoromethyl)phenyl)methanesulfonamide

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 12h;

Reference yield:

: C₉H₁₀F₃NO₄S₂

: 50790-31-3
N‐(2‐(trifluoromethyl)phenyl)methanesulfonamide

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 23 ℃; for 1h;
DOI:10.1016/S0040-4020(00)00549-4

Reference yield:

: 88-17-5
2-(trifluoromethyl)benzenamine

: 50790-31-3
N‐(2‐(trifluoromethyl)phenyl)methanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 12 h / 23 °C

2: NaOH / H₂O; tetrahydrofuran / 1 h / 23 °C

With pyridine; sodium hydroxide; In tetrahydrofuran; water; 1: Substitution / 2: Hydrolysis;
DOI:10.1016/S0040-4020(00)00549-4