Chemical Property of Flomoxef
Chemical Property:
- Melting Point:29-31°C(lit.)
- Refractive Index:1.731
- Boiling Point:232-233°C(lit.)
- Flash Point:>230°F
- PSA：219.60000
- Density:1.856 g/cm3
- LogP:-0.96180
- XLogP3:-1.3
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:14
- Rotatable Bond Count:11
- Exact Mass:496.06464561
- Heavy Atom Count:32
- Complexity:793
- Purity/Quality:
-
98%min *data from raw suppliers
Flomoxef *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:COC1(C2N(C1=O)C(=C(CO2)CSC3=NN=NN3CCO)C(=O)O)NC(=O)CSC(F)F
- Isomeric SMILES:CO[C@@]1([C@@H]2N(C1=O)C(=C(CO2)CSC3=NN=NN3CCO)C(=O)O)NC(=O)CSC(F)F
- Recent ClinicalTrials:An Efficacy and Safety of Flomoxef Versus Cefepime in the Treatment of Participants With Urinary Tract Infections
- Recent NIPH Clinical Trials:Study on pharmacokinetics of prophylactic antibiotics for surgical site infection by ESBL-producing Escherichia coli after lower gastrointestinal surgery
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Description
Flomoxef sodium is a P-lactamase resistant oxacephalosporin. Its spectrum of activity is
similar to that of cefazolin and moxalactam, but with better efficacy against
Staphylococcus aureus and Bacteroides fragilis. Flomoxef is reported effective in the
treatment of post-operative, urinary tract and abdominal cavity infections.
-
Uses
Flomoxef is an oxacephem derived beta-lactam antibiotic that is particularly effective against gram-positive bacteria.
