Technology Process of 2-(1-phenylcyclopentyl)acetamidine hydrochloride
There total 6 articles about 2-(1-phenylcyclopentyl)acetamidine hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trimethylaluminum; ammonium chloride;
In
toluene;
at 5 - 80 ℃;
for 14h;
Concentration;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: diisobutylaluminium hydride / toluene; dichloromethane / 2 h / -78 °C
2: sodium tetrahydroborate; methanol / 2 h / 0 - 20 °C
3: triethylamine / dichloromethane / 16 h / 0 - 20 °C
4: potassium iodide / dimethyl sulfoxide / 20 h / 20 - 140 °C
5: ammonium chloride; trimethylaluminum / toluene / 14 h / 5 - 80 °C
With
methanol; sodium tetrahydroborate; trimethylaluminum; diisobutylaluminium hydride; ammonium chloride; triethylamine; potassium iodide;
In
dichloromethane; dimethyl sulfoxide; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sodium hydride / diethyl ether; dimethyl sulfoxide / 3 h / 20 °C
2: diisobutylaluminium hydride / toluene; dichloromethane / 2 h / -78 °C
3: sodium tetrahydroborate; methanol / 2 h / 0 - 20 °C
4: triethylamine / dichloromethane / 16 h / 0 - 20 °C
5: potassium iodide / dimethyl sulfoxide / 20 h / 20 - 140 °C
6: ammonium chloride; trimethylaluminum / toluene / 14 h / 5 - 80 °C
With
methanol; sodium tetrahydroborate; trimethylaluminum; sodium hydride; diisobutylaluminium hydride; ammonium chloride; triethylamine; potassium iodide;
In
diethyl ether; dichloromethane; dimethyl sulfoxide; toluene;
