tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

Base Information

Chemical Name:tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
CAS No.:1240480-33-4
Molecular Formula:C₁₃H₁₆FNO₅S
Molecular Weight:317.338
Hs Code.:

Synonyms:tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

Suppliers and Price of tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

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Technology Process of tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

There total 6 articles about tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.5%

: 1035490-58-4
[(S)-1-(3-fluoro-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester

: 1240480-33-4
tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

Guidance literature:: [(S)-1-(3-fluoro-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester; With pyridine; thionyl chloride; In acetonitrile; at -40 - 20 ℃;

With sodium periodate; ruthenium(III) trichloride hydrate; In water; acetonitrile; at 20 ℃; for 18h;
DOI:10.1021/acs.jmedchem.1c01087

Reference yield: 39.0%

: 1240480-33-4
tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

Guidance literature:: With pyridine; thionyl chloride; In dichloromethane; at -40 ℃; for 2.5h; Inert atmosphere;

With ruthenium trichloride; sodium periodate; In water; acetonitrile; at 0 - 20 ℃; for 2.25h; Inert atmosphere;

Reference yield:

: C₁₃H₁₆FNO₄S

: 1240480-33-4
tert-butyl (S)-4-(3-fluorophenyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide

Guidance literature:: With ruthenium trichloride; sodium periodate; In water; acetonitrile; at 0 - 20 ℃; for 2.25h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b02335