5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide

Base Information

Chemical Name:5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide
CAS No.:1150103-10-8
Molecular Formula:C₁₈H₂₀FN₅O₂
Molecular Weight:357.388
Hs Code.:

Synonyms:5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide

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Chemical Property of 5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide

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Technology Process of 5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide

There total 2 articles about 5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1150103-08-4
1,1-dimethylethyl 4-[({[6-(aminocarbonyl)-3-pyridinyl]amino}carbonyl)(3-fluorophenyl)amino]-1-piperidinecarboxylate

: 1150103-10-8
5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide

Guidance literature:: 1,1-dimethylethyl 4-[({[6-(aminocarbonyl)-3-pyridinyl]amino}carbonyl)(3-fluorophenyl)amino]-1-piperidinecarboxylate; With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 2h;

With sodium carbonate; In water;

Reference yield: 100.0%

: 1150103-10-8
5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide

Guidance literature:

Reference yield: 62.0%

: 1150111-59-3
2-methyl-6-{[4-(4-morpholinylcarbonyl)phenyl]oxy}-3-pyridinecarbaldehyde

: 1150103-10-8
5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide

: 64-19-7,77671-22-8
acetic acid

: 5-{[((3-fluorophenyl){1-[(2-methyl-6-{[4-(4-morpholinylcarbonyl)phenyl]oxy}-3-pyridinyl)methyl]-4-piperidinyl}amino)carbonyl]amino}-2-pyridinecarboxamide acetate

Guidance literature:: 2-methyl-6-{[4-(4-morpholinylcarbonyl)phenyl]oxy}-3-pyridinecarbaldehyde; 5-({[(3-fluorophenyl)(4-piperidinyl)amino]carbonyl}amino)-2-pyridinecarboxamide; With sodium tris(acetoxy)borohydride; In dichloromethane; for 16h;

With water; potassium carbonate; In dichloromethane;

acetic acid; In ethyl acetate;