hydratropic acid N-ethoxyamide

Base Information

• Chemical Name: hydratropic acid N-ethoxyamide
• CAS No.: 151599-47-2
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.246
• Mol file: 151599-47-2.mol

Synonyms:hydratropic acid N-ethoxyamide

Chemical Property of hydratropic acid N-ethoxyamide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of hydratropic acid N-ethoxyamide

There total 1 articles about hydratropic acid N-ethoxyamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-phenylpropionyl chloride (25145-43-1,36240-11-6,59981-93-0,22414-26-2) + O-ethyl hydroxylamine (624-86-2) → hydratropic acid N-ethoxyamide (151599-47-2)

Guidance literature:

With triethylamine; In benzene; at 20 ℃; for 12h;

DOI:10.1007/BF00863370

Reference yield: 84.5%

hydratropic acid N-ethoxyamide (151599-47-2) → hydratropic acid N-ethoxyimidoyl chloride

Guidance literature:

With phosphorus pentachloride; In benzene; at 20 ℃; for 12h;

DOI:10.1007/BF00863370

Reference yield:

hydratropic acid N-ethoxyamide (151599-47-2) → 1-phenylethyl cyanide (1823-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 84.5 percent / PCl₅ / benzene / 12 h / 20 °C

2: t-BuOK / tetrahydrofuran / 12 h / 20 °C

With phosphorus pentachloride; potassium tert-butylate; In tetrahydrofuran; benzene;

DOI:10.1007/BF00863370

upstream raw materials:

2-phenylpropionyl chloride

O-ethyl hydroxylamine

Downstream raw materials:

1-phenylethyl cyanide