4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol

Base Information

• Chemical Name: 4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol
• CAS No.: 214854-34-9
• Molecular Formula: C₁₀H₁₀N₄O₂
• Molecular Weight: 218.215
• Mol file: 214854-34-9.mol

Synonyms:4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol

Chemical Property of 4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol

There total 3 articles about 4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-amino-1,2,4-triazole (584-13-4) + vanillin (121-33-5,8014-42-4) → 4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol (214854-34-9)

Guidance literature:

With sulfuric acid; In ethanol; water; for 3h; Reflux;

DOI:10.1039/c7ra10497a

Reference yield:

4-((2-(1H-tetrazol-5-yl)hydrazono)methyl)-2-methoxyphenol (56929-45-4) → 4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol (214854-34-9)

Guidance literature:

Multi-step reaction with 2 steps

1: laccase from Trametesversicolor; oxygen / ethanol / 2 h / 30 °C / pH 4.7 / Enzymatic reaction

2: sulfuric acid / ethanol; water / 3 h / Reflux

With sulfuric acid; laccase from Trametesversicolor; oxygen; In ethanol; water;

DOI:10.1039/c7ra10497a

Reference yield:

4-(hydrazonomethyl)-2-methoxyphenol (1527-84-0) → 4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol (214854-34-9)

Guidance literature:

Multi-step reaction with 2 steps

1: laccase from Trametesversicolor; oxygen / dimethyl sulfoxide / 16 h / 30 °C / pH 4.7 / Enzymatic reaction

2: sulfuric acid / ethanol; water / 3 h / Reflux

With sulfuric acid; laccase from Trametesversicolor; oxygen; In ethanol; water; dimethyl sulfoxide;

DOI:10.1039/c7ra10497a

upstream raw materials:

4-amino-1,2,4-triazole

vanillin

4-(hydrazonomethyl)-2-methoxyphenol

4-((2-(1H-tetrazol-5-yl)hydrazono)methyl)-2-methoxyphenol

Downstream raw materials:

C₁₂H₁₂N₄O₃S

C₁₈H₁₃Cl₂N₅O₃S

C₁₈H₁₅N₅O₃S

C₁₈H₁₄ClN₅O₃S