8-Fluoro-1-octanol

Base Information

• Chemical Name: 8-Fluoro-1-octanol
• CAS No.: 408-27-5
• Molecular Formula: C8H17FO
• Molecular Weight: 148.2184
• DSSTox Substance ID: DTXSID30961216
• Nikkaji Number: J49.356B
• Wikidata: Q82942580
• Mol file: 408-27-5.mol

Synonyms:8-fluorooctan-1-ol;8-Fluoro-1-octanol;408-27-5;1-OCTANOL, 8-FLUORO-;8-Fluorooctanol;omega-Fluorooctanol;BRN 1698110;4-01-00-01766 (Beilstein Handbook Reference);8-fluoro-octan-1-ol;C8H17FO;SCHEMBL2541526;DTXSID30961216;C8-H17-F-O;LS-98019

Chemical Property of 8-Fluoro-1-octanol

Chemical Property:

• Vapor Pressure: 0.0737mmHg at 25°C
• Boiling Point: 201.9°Cat760mmHg
• Flash Point: 105.8°C
• Density: 0.906g/cm³
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 148.126343324
• Heavy Atom Count: 10
• Complexity: 57.2

Purity/Quality:

99.0% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCCF)CCCO

Technology Process of 8-Fluoro-1-octanol

There total 4 articles about 8-Fluoro-1-octanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,8-Octanediol (629-41-4) → 8-fluoro-octan-1-ol (408-27-5)

Guidance literature:

Multi-step reaction with 2 steps

1: water; copper (I)-chloride; hydrochloric acid

2: diethylene glycol; potassium fluoride / 120 °C

With hydrogenchloride; potassium fluoride; water; copper(l) chloride; diethylene glycol;

DOI:10.1021/jo01113a006

Reference yield:

8-chlorooctan-1-ol (23144-52-7) → 8-fluoro-octan-1-ol (408-27-5)

Guidance literature:

With potassium fluoride; diethylene glycol; at 120 ℃;

DOI:10.1021/jo01113a006

Reference yield:

1-chloro-6-fluorohexane (1550-09-0) → 8-fluoro-octan-1-ol (408-27-5)

Guidance literature:

With diethyl ether; magnesium; Behandeln der Reaktionsloesung mit Aethylenoxid;

DOI:10.1021/jo01354a007

upstream raw materials:

1-chloro-6-fluorohexane

8-chlorooctan-1-ol

1,8-Octanediol

dimethyl subarate

Downstream raw materials:

1-chloro-8-fluorooctane

1-bromo-8-fluorooctane

1,14-Difluor-tetradecan

18‐fluorooctadecanoic acid