2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol

Base Information

Chemical Name:2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol
CAS No.:145192-09-2
Molecular Formula:C₂₂H₁₉Cl₃O₂
Molecular Weight:421.751
Hs Code.:

Synonyms:2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol

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Chemical Property of 2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol

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Technology Process of 2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol

There total 3 articles about 2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.7%

: 145192-06-9
2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)-1-(4-methoxyphenyl)-1-propanone

: 145192-09-2
2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Ambient temperature;
DOI:10.1016/0223-5234(92)90183-2

Reference yield:

: 52578-11-7
2-(4-chlorophenyl)-1-(4-methoxyphenyl)ethanone

: 145192-09-2
2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 98.9 percent / NaH / tetrahydrofuran / 1 h / Ambient temperature

2: 71.7 percent / LiAlH₄ / tetrahydrofuran / 2 h / Ambient temperature

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran;
DOI:10.1016/0223-5234(92)90183-2

Reference yield:

: 25026-34-0
4-chlorophenacetyl chloride

: 145192-09-2
2-(4-Chloro-phenyl)-3-(2,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / AlCl₃ / CH₂Cl₂ / 1 h / Ambient temperature

2: 98.9 percent / NaH / tetrahydrofuran / 1 h / Ambient temperature

3: 71.7 percent / LiAlH₄ / tetrahydrofuran / 2 h / Ambient temperature

With lithium aluminium tetrahydride; aluminium trichloride; sodium hydride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/0223-5234(92)90183-2