3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol

Base Information

Chemical Name:3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol
CAS No.:354-68-7
Molecular Formula:C₄H₈F₃NO
Molecular Weight:143.109
Hs Code.:
ChEMBL ID:CHEMBL4526416
DSSTox Substance ID:DTXSID00545204
Mol file:354-68-7.mol

Synonyms:3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol;354-68-7;SCHEMBL2371656;CHEMBL4526416;DTXSID00545204;AKOS006295554;CS-0276135;3-Amino-1,1,1-trifluoro-2-methyl-2-propanol;EN300-119131;3-amino-1,1,1-trifluoro-2-methyl-propan-2-ol;Q-101078;F8889-4617

Suppliers and Price of 3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol

Chemical Property:

Melting Point:70-71 °C
Boiling Point:183.2±40.0 °C(Predicted)
PKA:10.21±0.50(Predicted)
Density:1.275±0.06 g/cm3(Predicted)
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:143.05579836
Heavy Atom Count:9
Complexity:103

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CN)(C(F)(F)F)O

Technology Process of 3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol

There total 1 articles about 3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 428-70-6
1,1,1-trifluoro-2-methyl-3-nitropropan-2-ol

: 354-68-7
(±)-3-amino-1,1,1-trifluoro-2-methylpropan-2-ol

Guidance literature:: With hydrogen; nickel; In ethanol; for 12h; under 3750.3 Torr; Ambient temperature;

Reference yield:

: 85-44-9
phthalic anhydride

: 354-68-7
(±)-3-amino-1,1,1-trifluoro-2-methylpropan-2-ol

: 1334547-41-9
2-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)isoindoline-1,3-dione

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In chloroform; at 70 ℃; for 5h;

Reference yield:

: 100-52-7
benzaldehyde

: 354-68-7
(±)-3-amino-1,1,1-trifluoro-2-methylpropan-2-ol

: 3-(benzylamino)-1,1,1-trifluoro-2-methylpropan-2-ol

Guidance literature:: benzaldehyde; (±)-3-amino-1,1,1-trifluoro-2-methylpropan-2-ol; With N-ethyl-N,N-diisopropylamine; In methanol; at 110 ℃; for 8h; Microwave irradiation;

With methanol; sodium tetrahydroborate; at 0 - 25 ℃; for 72h;