C₁₆H₁₃NO₂

Base Information

• Chemical Name: C₁₆H₁₃NO₂
• CAS No.: 1310886-21-5
• Molecular Formula: C₁₆H₁₃NO₂
• Molecular Weight: 251.285
• Mol file: 1310886-21-5.mol

Synonyms:C₁₆H₁₃NO₂

Chemical Property of C₁₆H₁₃NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₆H₁₃NO₂

There total 1 articles about C₁₆H₁₃NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

1-methoxyindole-2-carboxaldehyde (3289-87-0) + ortho-cresol (95-48-7,77504-84-8) → C16H13NO2 (1310886-21-5)

Guidance literature:

With potassium tert-butylate; In tert-butyl alcohol; at 80 ℃; for 6h; Inert atmosphere;

DOI:10.1021/ol201194n

Reference yield:

C16H13NO2 (1310886-21-5) + benzyl bromide (100-39-0) → C23H19NO2

Guidance literature:

C₁₆H₁₃NO₂; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; Inert atmosphere;

benzyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol201194n

Reference yield:

C16H13NO2 (1310886-21-5) → C26H22N2O

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: benzene / 100 °C / Inert atmosphere

With sodium hydride; In N,N-dimethyl-formamide; benzene;

DOI:10.1021/ol201194n

upstream raw materials:

1-methoxyindole-2-carboxaldehyde

ortho-cresol

Downstream raw materials:

C₃₃H₃₀N₂O₃S

C₂₆H₂₃NO₂

C₃₃H₃₀N₂O₃S

C₂₆H₂₃NO₂