4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetraazapentacosyl)-2-(fluoromethyl)phenyl dihydrogen phosphate

Base Information

Chemical Name:4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetraazapentacosyl)-2-(fluoromethyl)phenyl dihydrogen phosphate
CAS No.:1258428-84-0
Molecular Formula:C₄₅H₆₆FN₈O₁₃PS
Molecular Weight:1009.1
Hs Code.:

4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetraazapentacosyl)-2-(fluoromethyl)phenyl dihydrogen phosphate

Synonyms:4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetraazapentacosyl)-2-(fluoromethyl)phenyl dihydrogen phosphate

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Chemical Property of 4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetraazapentacosyl)-2-(fluoromethyl)phenyl dihydrogen phosphate

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Technology Process of 4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetraazapentacosyl)-2-(fluoromethyl)phenyl dihydrogen phosphate

There total 1 articles about 4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetraazapentacosyl)-2-(fluoromethyl)phenyl dihydrogen phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1258428-89-5
diallyl (4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohex-ahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetra-azapentacosyl)-2-(fluoromethyl)phenyl)phosphate

: 1258428-84-0
4-((2S,5S)-2-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)carbamoyl)-5-benzyl-4,7,10,21-tetraoxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17-dioxa-3,6,11,20-tetraazapentacosyl)-2-(fluoromethyl)phenyl dihydrogen phosphate

Guidance literature:: With trimethylsilyl bromide; N,O-Bis(trimethylsilyl)trifluoroacetamide; In acetonitrile; at 20 ℃; Cooling with ice;
DOI:10.1016/j.tet.2010.04.065