gamma-Hydroxybenzenebutanal

Base Information

• Chemical Name: gamma-Hydroxybenzenebutanal
• CAS No.: 22927-17-9
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.204
• DSSTox Substance ID: DTXSID601313507
• Mol file: 22927-17-9.mol

Synonyms:gamma-Hydroxybenzenebutanal;SCHEMBL634044;DTXSID601313507;22927-17-9

Chemical Property of gamma-Hydroxybenzenebutanal

Chemical Property:

• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 164.083729621
• Heavy Atom Count: 12
• Complexity: 128

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(CCC=O)O

Technology Process of gamma-Hydroxybenzenebutanal

There total 6 articles about gamma-Hydroxybenzenebutanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenyl-3-(4,4,6-trimethyl-[1,3]oxazinan-2-yl)-propan-1-ol (22944-91-8) → 4-hydroxy-4-phenyl-butyraldehyde (22927-17-9)

Guidance literature:

With oxalic acid;

DOI:10.1021/ja01036a076

Reference yield:

1-phenyl-4-penten-1-ol (102632-99-5,134679-60-0,144178-31-4,54525-86-9) → 4-hydroxy-4-phenyl-butyraldehyde (22927-17-9)

Guidance literature:

With ozone; acetic acid; anschliessend bei der Reduktion mit Zinkstaub in Aether;

Reference yield:

1-Phenylpent-4-en-1-one (3240-29-7) → 4-hydroxy-4-phenyl-butyraldehyde (22927-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium; absolute alcohol

2: glacial acetic acid; ozone / anschliessend bei der Reduktion mit Zinkstaub in Aether

With ethanol; sodium; ozone; acetic acid;

upstream raw materials:

1-phenyl-4-penten-1-ol

styrene oxide

2,4,4,6-tetramethyl-5,6-dihydro-4H-1,3-oxazine

3-phenyl-3-(4,4,6-trimethyl-[1,3]oxazinan-2-yl)-propan-1-ol

Downstream raw materials:

3-Phenyltetrahydrofuran-2-ol

tetrahydro-2-methoxy-5-phenylfuran

succinylbenzene