Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester

Base Information

• Chemical Name: Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester
• CAS No.: 118270-65-8
• Molecular Formula: C₂₄H₂₂O₄Se
• Molecular Weight: 453.396
• Mol file: 118270-65-8.mol

Synonyms:Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester

Chemical Property of Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester

There total 1 articles about Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Phenylselenyl bromide (34837-55-3) + cinnamyl benzoate (5320-75-2) + acetic acid (64-19-7,77671-22-8) → Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester (118270-65-8)

Guidance literature:

With potassium acetate; acetic anhydride; for 15.5h; Ambient temperature;

DOI:10.1021/jo00265a031

Reference yield: 96.0%

Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester (118270-65-8) → <1-acetoxy-3-(benzoyloxy)-1-phenyl-2-propyl>phenylselenium dichloride (118270-74-9)

Guidance literature:

With sulfuryl dichloride; In chloroform; for 0.25h; Ambient temperature;

DOI:10.1021/jo00265a031

Reference yield:

Benzoic acid (2S,3R)-3-acetoxy-3-phenyl-2-phenylselanyl-propyl ester (118270-65-8) → Benzoic acid (Z)-3-acetoxy-3-phenyl-allyl ester (118270-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / SO₂Cl₂ / CHCl₃ / 0.25 h / Ambient temperature

2: NaHCO₃, water / CH₂Cl₂ / 24 h / Ambient temperature

With sulfuryl dichloride; water; sodium hydrogencarbonate; In dichloromethane; chloroform;

DOI:10.1021/jo00265a031

upstream raw materials:

Phenylselenyl bromide

cinnamyl benzoate

acetic acid

Downstream raw materials:

<1-acetoxy-3-(benzoyloxy)-1-phenyl-2-propyl>phenylselenium dichloride

Benzoic acid (Z)-3-acetoxy-3-phenyl-allyl ester