Δ5-hexadecenol

Base Information

• Chemical Name: Δ5-hexadecenol
• CAS No.: 106463-48-3
• Molecular Formula: C₁₆H₃₂O
• Molecular Weight: 240.429
• Mol file: 106463-48-3.mol

Synonyms:Δ5-hexadecenol

Chemical Property of Δ5-hexadecenol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Δ5-hexadecenol

There total 6 articles about Δ5-hexadecenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.8%

(Z)-hexadec-5-ene (69820-25-3) → (Z)-11-hexadecen-1-ol (56683-54-6) + Δ5-hexadecenol (106463-48-3)

Guidance literature:

With CYP₅₂A₁₃ hydroxylase enzyme; oxygen; In water; at 30 ℃; Reagent/catalyst;

Reference yield:

1-dodecene (112-41-4,25067-08-7,62132-67-6) → (Z)-11-hexadecen-1-ol (56683-54-6) + Δ5-hexadecenol (106463-48-3)

Guidance literature:

Multi-step reaction with 2 steps

1: [2-(1-methylethoxy-O)phenylmethyl-C](nitrato-O,O′){rel-(2R,5R,7R)-adamantane-2,1-diyl[3-(2,4,6-trimethylphenyl)-1-imidazolidinyl-2-ylidene]}ruthenium / Heating

2: oxygen; CYP₅₂A₁₃ hydroxylase enzyme / water / 30 °C

With CYP₅₂A₁₃ hydroxylase enzyme; [2-(1-methylethoxy-O)phenylmethyl-C](nitrato-O,O′){rel-(2R,5R,7R)-adamantane-2,1-diyl[3-(2,4,6-trimethylphenyl)-1-imidazolidinyl-2-ylidene]}ruthenium; oxygen; In water;

Reference yield:

hex-1-yne (693-02-7) → (Z)-11-hexadecen-1-ol (56683-54-6) + Δ5-hexadecenol (106463-48-3)

Guidance literature:

Multi-step reaction with 3 steps

1: n-butyllithium; tetra-(n-butyl)ammonium iodide / tetrahydrofuran; hexane / 24 h / -78 - 70 °C

2: hydrogen; quinoline / pentane / 18 h / 0 - 20 °C

3: oxygen; CYP₅₂A₁₃ hydroxylase enzyme / water / 30 °C

With quinoline; n-butyllithium; CYP₅₂A₁₃ hydroxylase enzyme; hydrogen; oxygen; tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; hexane; water; pentane;

upstream raw materials:

1-dodecene

hex-1-yne

1-dodecyne

1-bromo dodecane

Refernces