3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone

Base Information

• Chemical Name: 3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone
• CAS No.: 55395-02-3
• Molecular Formula: C₂₃H₂₄O₆
• Molecular Weight: 396.44
• Mol file: 55395-02-3.mol

Synonyms:3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone

Chemical Property of 3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone

There total 8 articles about 3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5-hydroxy-3-methoxy-2-(4-methoxyphenyl)-7,8-(2,2-dimethyl-2H-pyran)-4H-chromen-4-one (55395-01-2) + dimethyl sulfate (77-78-1) → 3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone (55395-02-3)

Guidance literature:

5-hydroxy-3-methoxy-2-(4-methoxyphenyl)-7,8-(2,2-dimethyl-2H-pyran)-4H-chromen-4-one; With potassium carbonate; In acetone; at 20 ℃; for 0.166667h;

dimethyl sulfate; In acetone; for 48h; Reflux;

DOI:10.1080/14786419.2020.1844686

Reference yield: 85.0%

5-hydroxy-3-methoxy-2-(4-methoxyphenyl)-7,8-(2,2-dimethyl-2H-pyran)-4H-chromen-4-one (55395-01-2) + methyl iodide (74-88-4) → 3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone (55395-02-3)

Guidance literature:

5-hydroxy-3-methoxy-2-(4-methoxyphenyl)-7,8-(2,2-dimethyl-2H-pyran)-4H-chromen-4-one; With potassium carbonate; In acetone; at 20 ℃; for 0.166667h;

methyl iodide; In acetone; for 6.16667h; Reflux;

Reference yield:

→ 3,5,4'-trimethoxy-6'',6''-dimethyldihydropyrano<2'',3'':7,8>flavone (55395-02-3)

Guidance literature:

With potassium hydroxide; dimethyl sulfate;

upstream raw materials:

3,5-dihydroxy-2-(4-methoxyphenyl)-8,8-dimethyl-9,10-dihydro-8H-pyrano[2,3-f]chromen-4-one

methyl iodide

icaritin

5-hydroxy-3-methoxy-2-(4-methoxyphenyl)-7,8-(2,2-dimethyl-2H-pyran)-4H-chromen-4-one

Downstream raw materials:

5-Hydroxy-7-methoxy-6-methoxyacetyl-2,2-dimethyl-2H-1-benzopyran

4-methoxybenzoic acid