phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

Base Information

Chemical Name:phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside
CAS No.:277757-07-0
Molecular Formula:C₇₀H₆₉NO₁₁SSi
Molecular Weight:1160.47
Hs Code.:

phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

Synonyms:phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

Suppliers and Price of phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

There total 11 articles about phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 277310-81-3
3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranosyl fluoride

: 277757-06-9
phenyl 2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-this-α-D-mannopyranoside

: 277757-07-0
phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

Guidance literature:: With zirconocene dichloride; MS 4 Angstroem; silver trifluoromethanesulfonate; In dichloromethane; at -40 ℃; for 2h;
DOI:10.1002/(SICI)1099-0690(200004)2000:8<1547::AID-EJOC1547<3.0.CO;2-C

Reference yield:

: 100-39-0
benzyl bromide

: 277757-07-0
phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: 100 percent / NaH / dimethylformamide / 2 h / 25 °C

2: 79 percent / F₃CSO₃SiMe / 3 h / 0 - 25 °C

3: 98 percent / TFA / CH₂Cl₂ / 3 h / 25 °C

4: 89 percent / imidazole / DMAP / dimethylformamide / 17 h / 25 °C

5: BF₃*Et₂O / CH₂Cl₂ / 30 h / 25 °C

6: 100 percent / NaOMe / methanol / 1 h / 25 °C

7: 82 percent / Cp₂ZrCl₂; CF₃SO₃Ag; MS 4 Angstroem / CH₂Cl₂ / 2 h / -40 °C

With 1H-imidazole; zirconocene dichloride; MS 4 Angstroem; boron trifluoride diethyl etherate; sodium methylate; silver trifluoromethanesulfonate; sodium hydride; trifluoroacetic acid; dmap; In methanol; dichloromethane; N,N-dimethyl-formamide; 1: Alkylation / 2: Ring cleavage / 3: Decomposition / 4: silylation / 5: Substitution / 6: Deacetylation / 7: Etherification;
DOI:10.1002/(SICI)1099-0690(200004)2000:8<1547::AID-EJOC1547<3.0.CO;2-C

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 277757-07-0
phenyl O-(3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-α-D-glucopyranosyl)-(1->6)-2,4-di-O-benzyl-3-O-(tert-butyldiphenylsilyl)-1-thio-α-D-mannopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / imidazole / DMAP / dimethylformamide / 17 h / 25 °C

2: BF₃*Et₂O / CH₂Cl₂ / 30 h / 25 °C

3: 100 percent / NaOMe / methanol / 1 h / 25 °C

4: 82 percent / Cp₂ZrCl₂; CF₃SO₃Ag; MS 4 Angstroem / CH₂Cl₂ / 2 h / -40 °C

With 1H-imidazole; zirconocene dichloride; MS 4 Angstroem; boron trifluoride diethyl etherate; sodium methylate; silver trifluoromethanesulfonate; dmap; In methanol; dichloromethane; N,N-dimethyl-formamide; 1: silylation / 2: Substitution / 3: Deacetylation / 4: Etherification;
DOI:10.1002/(SICI)1099-0690(200004)2000:8<1547::AID-EJOC1547<3.0.CO;2-C