1-(2-chloro-5-(methylthio)phenyl)-3-⁽¹¹⁾C-methyl-3-(3-(difluoromethoxy)phenyl)guanidine

Base Information

• Chemical Name: 1-(2-chloro-5-(methylthio)phenyl)-3-⁽¹¹⁾C-methyl-3-(3-(difluoromethoxy)phenyl)guanidine
• CAS No.: 1415399-09-5
• Molecular Formula: C₁₆H₁₆ClF₂N₃OS
• Molecular Weight: 370.827

Synonyms:1-(2-chloro-5-(methylthio)phenyl)-3-⁽¹¹⁾C-methyl-3-(3-(difluoromethoxy)phenyl)guanidine

Chemical Property of 1-(2-chloro-5-(methylthio)phenyl)-3-⁽¹¹⁾C-methyl-3-(3-(difluoromethoxy)phenyl)guanidine

Chemical Property:

Purity/Quality:

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Technology Process of 1-(2-chloro-5-(methylthio)phenyl)-3-⁽¹¹⁾C-methyl-3-(3-(difluoromethoxy)phenyl)guanidine

There total 2 articles about 1-(2-chloro-5-(methylthio)phenyl)-3-⁽¹¹⁾C-methyl-3-(3-(difluoromethoxy)phenyl)guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[11C]methyl iodide (54245-42-0) + 1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)guanidine (1415399-00-6) → 1-(2-chloro-5-(methylthio)phenyl)-3-(11)C-methyl-3-(3-(difluoromethoxy)phenyl)guanidine (1415399-09-5)

Guidance literature:

sodium hydroxide; In water; N,N-dimethyl-formamide; at 80 ℃; for 0.05h;

Reference yield:

[11C]methyl iodide (54245-42-0) + 1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)guanidine (1415399-00-6) → 1-(2-chloro-5-(methylthio)phenyl)-3-(11)C-methyl-3-(3-(difluoromethoxy)phenyl)guanidine (1415399-09-5) + C15(11)CH16ClF2N3OS

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; at 80 ℃; for 0.05h; Reagent/catalyst; Solvent;

DOI:10.1016/j.bmc.2014.12.029

upstream raw materials:

[11C]methyl iodide

1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)guanidine

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