3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester

Base Information

• Chemical Name: 3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester
• CAS No.: 147524-80-9
• Molecular Formula: C₁₁H₁₃Cl₂NO₂
• Molecular Weight: 262.136
• Mol file: 147524-80-9.mol

Synonyms:3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester

Chemical Property of 3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester

There total 3 articles about 3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dichlorobenzaldehyde (10203-08-4) + ethylmalonic acid (601-75-2) → 3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester (147524-80-9)

Guidance literature:

With ammonium acetate; In ethanol; water; acetonitrile;

Reference yield:

3,5-dichlorobenzaldehyde (10203-08-4) → 3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester (147524-80-9)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium acetate / propan-2-ol / Heating

2: HCl

With ammonium acetate; hydrogenchloride; In isopropyl alcohol;

DOI:10.1016/j.bmc.2007.03.034

Reference yield:

ethanol (64-17-5) + (+/-)-3-amino-3-(3,5-dichlorophenyl)propanoic acid (188812-95-5,1080673-41-1) → 3-amino-3-(3,5-dichloro-phenyl)-propionic acid ethyl ester (147524-80-9)

Guidance literature:

With hydrogenchloride;

DOI:10.1016/j.bmc.2007.03.034

upstream raw materials:

ethanol

(+/-)-3-amino-3-(3,5-dichlorophenyl)propanoic acid

3,5-dichlorobenzaldehyde

ethylmalonic acid

Downstream raw materials:

ethyl (R)-3-amino-3-(3,5-dichlorophenyl)propanoate

(S)-3-amino-3-(3,5-dichlorophenyl)propanoic acid