Technology Process of C17H25FO2
There total 6 articles about C17H25FO2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C14H19FO;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 0.5h;
Inert atmosphere;
2-Bromoethyl methyl ether;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 4h;
Inert atmosphere;
DOI:10.1021/ja5026485
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
2.1: manganese(IV) oxide / dichloromethane / 20 h / 20 °C / Inert atmosphere
3.1: titanium tetrachloride / dichloromethane / 0.75 h / -78 - 20 °C / Inert atmosphere
4.1: (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole; benzo[1,3,2]dioxaborole / toluene / 24 h / -70 °C / Inert atmosphere
5.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere
5.2: 4 h / 0 - 20 °C / Inert atmosphere
With
manganese(IV) oxide; titanium tetrachloride; sodium hydride; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole; benzo[1,3,2]dioxaborole;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
3.1: |Hosomi-Sakurai Reaction;
DOI:10.1021/ja5026485
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: manganese(IV) oxide / dichloromethane / 20 h / 20 °C / Inert atmosphere
2.1: titanium tetrachloride / dichloromethane / 0.75 h / -78 - 20 °C / Inert atmosphere
3.1: (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole; benzo[1,3,2]dioxaborole / toluene / 24 h / -70 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere
4.2: 4 h / 0 - 20 °C / Inert atmosphere
With
manganese(IV) oxide; titanium tetrachloride; sodium hydride; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole; benzo[1,3,2]dioxaborole;
In
dichloromethane; N,N-dimethyl-formamide; toluene;
2.1: |Hosomi-Sakurai Reaction;
DOI:10.1021/ja5026485