4-bromo-2,5-dimethoxy-benzoic acid methyl ester

Base Information

Chemical Name:4-bromo-2,5-dimethoxy-benzoic acid methyl ester
CAS No.:855749-57-4
Molecular Formula:C₁₀H₁₁BrO₄
Molecular Weight:275.099
Hs Code.:

Synonyms:4-bromo-2,5-dimethoxy-benzoic acid methyl ester

Suppliers and Price of 4-bromo-2,5-dimethoxy-benzoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of 4-bromo-2,5-dimethoxy-benzoic acid methyl ester

Chemical Property:

Purity/Quality:: HPLC≥98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-bromo-2,5-dimethoxy-benzoic acid methyl ester

There total 1 articles about 4-bromo-2,5-dimethoxy-benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 2674-34-2
1,4-dibromo-2,5-dimethoxybenzene

: 15719-64-9,15719-76-3,97762-63-5
methylammonium carbonate

: 855749-57-4
4-bromo-2,5-dimethoxy-benzoic acid methyl ester

Guidance literature:: Reaktion ueber mehrere Stufen;

Reference yield: 50.0%

: 541-58-2
2,4-dimethylthiazole

: 855749-57-4
4-bromo-2,5-dimethoxy-benzoic acid methyl ester

: 1-(4-bromo-2,5-dimethoxyphenyl)-2-(4-methylthiazol-2-yl)ethan-1-one

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere; Cooling;
DOI:10.1002/anie.202003788

Reference yield:

: 855749-57-4
4-bromo-2,5-dimethoxy-benzoic acid methyl ester

: 1-(2,5-dimethoxy-4-propylphenyl)-2-(4-methylthiazol-2-yl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere; Cooling

2.1: dichlorobis(tri-O-tolylphosphine)palladium; tris-(o-tolyl)phosphine; diethylamine / tetrahydrofuran / 0.25 h / Inert atmosphere; Sealed tube

2.2: 12 h / 100 °C / Inert atmosphere; Sealed tube

With dichlorobis(tri-O-tolylphosphine)palladium; diethylamine; tris-(o-tolyl)phosphine; lithium hexamethyldisilazane; In tetrahydrofuran;
DOI:10.1002/anie.202003788