1,4-Dibromo-2,5-dimethoxybenzene

Base Information

• Chemical Name: 1,4-Dibromo-2,5-dimethoxybenzene
• CAS No.: 2674-34-2
• Molecular Formula: C8H8Br2O2
• Molecular Weight: 295.958
• Hs Code.: 2909309090
• European Community (EC) Number: 629-351-3
• NSC Number: 27013
• DSSTox Substance ID: DTXSID00282647
• Nikkaji Number: J265.488A
• Wikidata: Q72464184
• Mol file: 2674-34-2.mol

Synonyms:1,4-Dibromo-2,5-dimethoxybenzene;2674-34-2;2,5-DIBROMO-1,4-DIMETHOXYBENZENE;Benzene, 1,4-dibromo-2,5-dimethoxy-;MFCD00025694;NSC27013;1,4-Dibromo-2,5-dimethoxybenezene;1,4-dibromo-2,5-dimethoxy-benzene;2,5-Dibromohydroquinone Dimethyl Ether;Maybridge1_005131;SCHEMBL298224;2,5-Dibromo-4-methoxyanisole;HMS556B05;DTXSID00282647;1,4-Dibromo-3,6-dimethoxybenzene;2,5-Dimethoxy-1,4-dibromobenzene;AMY41113;CAA67434;1,4-dibromo-2,5-dimethoxy benzene;CL8581;NSC-27013;AKOS015851912;CS-W009180;PS-7156;BP-20278;SY030985;1,4-Dibromo-2,5-dimethoxybenzene, 97%;D3966;FT-0610280;EN300-160240;A818580;J-503982;Z1269241582;3-AMINO-3-(4-DIFLUOROMETHOXY-PHENYL)-PROPIONICACID;InChI=1/C8H8Br2O2/c1-11-7-3-6(10)8(12-2)4-5(7)9/h3-4H,1-2H

Chemical Property of 1,4-Dibromo-2,5-dimethoxybenzene

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 0.00364mmHg at 25°C
• Melting Point: 144-147 °C
• Refractive Index: 1.561
• Boiling Point: 290.3 °C at 760 mmHg
• Flash Point: 116.1 °C
• PSA: 18.46000
• Density: 1.743 g/cm³
• LogP: 3.22880
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Insoluble in water.
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 295.88706
• Heavy Atom Count: 12
• Complexity: 127

Purity/Quality:

99% ^*data from raw suppliers

1,4-Dibromo-2,5-dimethoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1Br)OC)Br
• Uses: 1,4-Dibromo-2,5-dimethoxybenzene was used in the preparation of poly[(9,9-bis(6-(dibromohexyl)-2,7-fluorene))-alt-1,4-(2,5-dimethoxybenzene)], a water-soluble polyfluorene derivative.

Technology Process of 1,4-Dibromo-2,5-dimethoxybenzene

There total 14 articles about 1,4-Dibromo-2,5-dimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,4-dimethoxybezene (150-78-7) → 1,4-dibromo-2,5-dimethoxybenzene (2674-34-2)

Guidance literature:

With hydrogen bromide; dihydrogen peroxide; In methanol; Heating;

DOI:10.1016/S0040-4020(99)00628-6

Reference yield: 95.0%

2,5-dibromohydroquinone (14753-51-6) + dimethyl sulfate (77-78-1) → 1,4-dibromo-2,5-dimethoxybenzene (2674-34-2)

Guidance literature:

With potassium carbonate; In acetone; for 6h; Reflux;

DOI:10.1039/c6dt03086f

Reference yield: 80.0%

2,5-dibromohydroquinone (14753-51-6) + methyl iodide (74-88-4) → 1,4-dibromo-2,5-dimethoxybenzene (2674-34-2)

Guidance literature:

2,5-dibromohydroquinone; With potassium hydroxide; In dimethyl sulfoxide; for 0.0833333h;

methyl iodide; In dimethyl sulfoxide; at 75 ℃;

DOI:10.1039/c3ce26494g

upstream raw materials:

4-methoxy-phenol

2,5-dibromohydroquinone

dimethyl sulfate

2,5-dibromo-4-methoxyphenol

Downstream raw materials:

1,4-Dibromo-3,3,6,6-tetramethoxy-cyclohexa-1,4-diene

(E,E)-1,4-bis(3,3-dimethoxy-1-propenyl)-2,5-dimethoxybenzene

((2,5-dimethoxy-1,4-phenylene)bis(ethyne-2,1-diyl))dibenzene

1,4-dimethoxy-2,5-bis(trideuteriomethyl)benzene

Refernces

• 1、 -. "NON-LINEAR CHROMOPHORE, PHOTOREFRACTIVE COMPOSITE COMPRISING THE SAME AND PHOTOREFRACTIVE DEVICE". Paragraph 0084-0087. . Retrieved 2021/02/05.
• 2、 Chen, Xiong,Feng, Xiao,Han, Songjie,Li, Chunzhi,Li, He,Li, Ziping,Liu, Xiaoming,Shao, Pengpeng,Xia, Hong. "Screening metal-free photocatalysts from isomorphic covalent organic frameworks for the C-3 functionalization of indoles". supporting information. p. 8706 - 8715. Retrieved 2020/05/16.