((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester

Base Information

Chemical Name:((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester
CAS No.:931093-21-9
Molecular Formula:C₁₉H₂₆N₄O₄
Molecular Weight:374.44
Hs Code.:

Synonyms:((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester

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Chemical Property of ((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester

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Technology Process of ((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester

There total 1 articles about ((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 931093-20-8
[(1R)-1-(4-{[5-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methoxypyrazinyl]oxy}phenyl)ethyl]methylcarbamic acid, 1,1-dimethylethyl ester

: 931093-21-9
((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester

Guidance literature:: With hydroxylamine hydrochloride; triethylamine; In water; isopropyl alcohol; Heating / reflux;

Reference yield:

: 931093-21-9
((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester

: 82417-45-6
dichlorobenzenesulfonyl chloride

: 2,3-dichloro-N-(3-methoxy-5-{4-[(1R)-1-(methylamino)ethyl]phenoxy}pyrazinyl)benzenesulphonamide trifluoroacetic acid salt

Guidance literature:: ((1R)-1-{4-[(5-amino-6-methoxypyrazinyl)oxy]phenyl}ethyl)methylcarbamic acid, 1,1-dimethylethyl ester; dichlorobenzenesulfonyl chloride; With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 0.666667h;

With hydrogenchloride; In tetrahydrofuran; water;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;