1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate

Base Information

Chemical Name:1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate
CAS No.:1008131-75-6
Molecular Formula:C₆₃H₆₂N₆O₉
Molecular Weight:1047.22
Hs Code.:

1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate

Synonyms:1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate

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Chemical Property of 1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate

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Technology Process of 1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate

There total 2 articles about 1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1008131-74-5
1,1-dimethylethyl (S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylcarbamate

: 132388-68-2
N^α-tert-butoxycarbonyl-N^ω-triphenylmethyl-L-asparagine

: 1008131-75-6
1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate

Guidance literature:: 1,1-dimethylethyl (S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylcarbamate; With hydrogenchloride; water; In isopropyl alcohol; at 50 ℃; for 3h;

N^α-tert-butoxycarbonyl-N^ω-triphenylmethyl-L-asparagine; With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 42h;
DOI:10.1021/jo901466b

Reference yield:

: C₃₅H₃₄N₄O₅

: 132388-68-2
N^α-tert-butoxycarbonyl-N^ω-triphenylmethyl-L-asparagine

: 1008131-75-6
1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 48h;
DOI:10.1021/jo702286b

Reference yield: 86.0%

: 1008131-75-6
1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate

: 13734-38-8,20887-86-9
N-(t-butyloxycarbonyl)-O-(t-butyl)-L-Serine

: 1190430-56-8
(6S,9S,12S,15S)-6-(tert-butoxymethyl)-2,2-dimethyl-4,7,10,13,16-pentaoxo-16-(2-oxooxazolidin-3-yl)-9,12-di-[2-oxo-2-(triphenylmethylamino)ethyl]-15-phenylmethyl-3-oxa-5,8,11,14-tetraaza-hexadecane

Guidance literature:: 1,1-dimethylethyl (S)-1-{(S)-1,4-dioxo-1-[(S)-1-oxo-1-(2-oxo-3-oxazolidinyl)-3-phenylpropan-2-ylamino]-4-(triphenylmethylamino)butan-2-ylamino}-1,4-dioxo-4-(triphenylmethylamino)butan-2-ylcarbamate; With hydrogenchloride; water; In isopropyl alcohol; at 50 ℃; for 3h;

N-(t-butyloxycarbonyl)-O-(t-butyl)-L-Serine; With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 18h;
DOI:10.1021/jo901466b