132388-68-2

Basic information

• Product Name: Boc-N-beta-Trityl-L-asparagine
• Synonyms: NALPHA-TERT-BUTOXYCARBONYL-NGAMMA-TRITYL-L-ASPARAGINE;N-ALPHA-T-BUTOXYCARBONYL-N-BETA-TRITYL-L-ASPARAGINE;N-ALPHA-T-BOC-N-BETA-TRITYL-ASPARAGINE;N-ALPHA-T-BOC-BETA-TRITYL-L-ASPARAGINE;n(alpha)-boc-n(gamma)-trityl-l-aspara-gine;Nα-Boc-Nγ-trityl-L-asparagine ;N-α-Boc-N-γ-trityl-L-asparagine;N-BETA-TERT-BUTOXYCARBONYL-N-GAMMA-TRITYL-L-ASPARAGINE
• CAS NO: 132388-68-2
• Molecular Formula: C₂₈H₃₀N₂O₅
• Molecular Weight: 474.55
• EINECS: 2017-001-1
• Product Categories: Asparagine [Asn, N];Boc-Amino Acids and Derivative;Boc-Amino acid series
• Mol File: 132388-68-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: ~205 °C (dec.)
• Boiling Point: 711 °C at 760 mmHg
• Flash Point: 383.8 °C
• Appearance: /
• Density: 1.202 g/cm³
• Vapor Pressure: 3.22E-21mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: Store at 0°C
• CAS DataBase Reference: Boc-N-beta-Trityl-L-asparagine(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-N-beta-Trityl-L-asparagine(132388-68-2)
• EPA Substance Registry System: Boc-N-beta-Trityl-L-asparagine(132388-68-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 132388-68-2(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Boc-Asn(Trt)-OH

InChI:InChI=1/C28H30N2O5/c1-27(2,3)35-26(34)29-23(25(32)33)19-24(31)30-28(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t23-/m0/s1

Upstream product

• 76-84-6 triphenylmethyl alcohol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 132388-58-0 (S)-2-Amino-N-trityl-succinamic acid 
• 132388-57-9 N-benzyloxycarbonyl-N'-trityl-L-asparagine 

Downstream Products

• 864238-58-4 (S)-2-[((1R,2R)-2-{(1S,2S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(trityl-carbamoyl)-propionylamino]-1-hydroxy-4-methyl-pentyl}-cyclopentanecarbonyl)-amino]-propionic acid benzyl ester 
• 864239-09-8 (S)-2-{(2R,4S,5S)-4-Benzyloxy-5-[(S)-2-tert-butoxycarbonylamino-3-(trityl-carbamoyl)-propionylamino]-2,7-dimethyl-octanoylamino}-propionic acid benzyl ester 
• 864238-57-3 (S)-2-{(S)-2-[((1R,2R)-2-{(1S,2S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(trityl-carbamoyl)-propionylamino]-1-hydroxy-4-methyl-pentyl}-cyclopentanecarbonyl)-amino]-propionylamino}-pentanedioic acid dibenzyl ester 
• 864238-56-2 4-(1-benzyloxycarbonyl-2-phenyl-ethylcarbamoyl)-4-{2-[(2-{2-[2-tert-butoxycarbonylamino-3-(trityl-carbamoyl)-propionylamino]-1-hydroxy-4-methyl-pentyl}-cyclopentanecarbonyl)-amino]-propionylamino}-butyric acid benzyl ester 
• 125882-62-4 fellutamide B 
• 129288-30-8 N-trityl 2-[(S)-2,5-dioxooxazolidin-4-yl]acetamide 

Relevant articles and documents

Protected amino acids and process for the preparation thereof

Compounds of the formula I, STR1 in which 'R1 is an amino protective group, and n stands for 1 or 2, R1 denotes hydrogen or an amino protective group, R2 denotes hydrogen or a carboxyl protective group and R3 denotes triphenylmethyl, 4-monomethoxy-trityl or 4,4'-dimethoxy-trityl, and reactive carboxylic acid derivatives of such compounds of the formula I in which R2 stands for hydrogen, are described. These compounds can be used as starting materials for the preparation of peptides. They are more suitable for this than are analogous compounds of the formula I in which R3 denotes hydrogen or one of the carbamoyl protective groups hitherto customary.