4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol

Base Information

Chemical Name:4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol
CAS No.:955092-74-7
Molecular Formula:C₁₉H₂₁ClN₄O₃
Molecular Weight:388.854
Hs Code.:

Synonyms:4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol

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Chemical Property of 4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol

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Technology Process of 4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol

There total 1 articles about 4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 27631-29-4
2-chloro-6,7-dimethoxy-3H-quinazolin-4-one

: 13886-04-9
N-(3-((dimethylamino)methyl)-4-hydroxyphenyl)acetamide

: 955092-74-7
4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol

Guidance literature:: N-(3-((dimethylamino)methyl)-4-hydroxyphenyl)acetamide; With hydrogenchloride; for 10h; Heating;

2-chloro-6,7-dimethoxy-3H-quinazolin-4-one; In ethanol; at 20 ℃; for 10h; Further stages.;
DOI:10.1016/j.bmc.2007.07.053

Reference yield: 95.0%

: 955092-74-7
4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol

: 74-88-4
methyl iodide

: 955092-71-4
(5-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-hydroxyphenyl)-N,N,N-trimethylmethanaminium iodide

Guidance literature:: In acetonitrile; at 20 ℃; for 12h;
DOI:10.1016/j.bmc.2007.07.053

Reference yield: 60.0%

: 955092-74-7
4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol

: 13886-04-9
N-(3-((dimethylamino)methyl)-4-hydroxyphenyl)acetamide

: 955092-75-8
C₂₈H₃₄N₆O₄

Guidance literature:: N-(3-((dimethylamino)methyl)-4-hydroxyphenyl)acetamide; With hydrogenchloride; for 10h; Heating;

4-(2-chloro-6,7-dimethoxyquinazolin-4-ylamino)-2-((dimethylamino)methyl)phenol; In ethanol; for 24h; Further stages.; Heating;
DOI:10.1016/j.bmc.2007.07.053