Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine

Base Information

• Chemical Name: Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine
• CAS No.: 111794-98-0
• Molecular Formula: C₁₉H₂₇NO
• Molecular Weight: 285.429
• Mol file: 111794-98-0.mol

Synonyms:Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine

Chemical Property of Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine

There total 3 articles about Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide (111794-97-9) → Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine (111794-98-0)

Guidance literature:

With diisobutylaluminium hydride;

DOI:10.1021/jo00235a020

Reference yield:

ethyl 2-ethoxycyclopent-1-ene-carboxylate (23153-72-2) → Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine (111794-98-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / 2.) potassium bis(trimethylsilyl)amide

2: 95 percent / lithium benzylamide / tetrahydrofuran

3: 85 percent / diisobutylaluminium hydride

With potassium hexamethylsilazane; lithium benzylamide; diisobutylaluminium hydride; In tetrahydrofuran;

DOI:10.1021/jo00235a020

Reference yield:

Ethyl 2-Ethoxy-1-(2-methyl-2-propenyl)-2-cyclopentene-1-carboxylate (111794-96-8) → Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine (111794-98-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / lithium benzylamide / tetrahydrofuran

2: 85 percent / diisobutylaluminium hydride

With lithium benzylamide; diisobutylaluminium hydride; In tetrahydrofuran;

DOI:10.1021/jo00235a020

upstream raw materials:

2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide

ethyl 2-ethoxycyclopent-1-ene-carboxylate

Ethyl 2-Ethoxy-1-(2-methyl-2-propenyl)-2-cyclopentene-1-carboxylate

Downstream raw materials:

2,5-Dibromo-pentanoic acid benzyl-[1-(2-methyl-allyl)-2-oxo-cyclopentylmethyl]-amide

(4aR,7aS)-2-Benzyl-4-(3-bromo-propyl)-4a-hydroxy-7a-(2-methyl-allyl)-octahydro-[2]pyrindin-3-one

(3aR,10aS)-5-Benzyl-3a-(2-methyl-allyl)-decahydro-10-oxa-5-aza-cyclopenta[d]naphthalen-6-one