2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide

Base Information

• Chemical Name: 2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide
• CAS No.: 111794-97-9
• Molecular Formula: C₁₉H₂₅NO₂
• Molecular Weight: 299.413
• Mol file: 111794-97-9.mol

Synonyms:2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide

Chemical Property of 2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide

There total 2 articles about 2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Ethyl 2-Ethoxy-1-(2-methyl-2-propenyl)-2-cyclopentene-1-carboxylate (111794-96-8) → 2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide (111794-97-9)

Guidance literature:

With lithium benzylamide; In tetrahydrofuran;

DOI:10.1021/jo00235a020

Reference yield:

ethyl 2-ethoxycyclopent-1-ene-carboxylate (23153-72-2) → 2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide (111794-97-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / 2.) potassium bis(trimethylsilyl)amide

2: 95 percent / lithium benzylamide / tetrahydrofuran

With potassium hexamethylsilazane; lithium benzylamide; In tetrahydrofuran;

DOI:10.1021/jo00235a020

Reference yield: 85.0%

2-Ethoxy-1-(2-methyl-allyl)-cyclopent-2-enecarboxylic acid benzylamide (111794-97-9) → Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine (111794-98-0)

Guidance literature:

With diisobutylaluminium hydride;

DOI:10.1021/jo00235a020

upstream raw materials:

Ethyl 2-Ethoxy-1-(2-methyl-2-propenyl)-2-cyclopentene-1-carboxylate

ethyl 2-ethoxycyclopent-1-ene-carboxylate

Downstream raw materials:

Benzyl-[2-ethoxy-1-(2-methyl-allyl)-cyclopent-2-enylmethyl]-amine

(3aR,10aS)-5-Benzyl-3a-(2-methyl-allyl)-decahydro-10-oxa-5-aza-cyclopenta[d]naphthalen-6-one

(4aR,7aS)-2-Benzyl-4-(3-bromo-propyl)-4a-hydroxy-7a-(2-methyl-allyl)-octahydro-[2]pyrindin-3-one

2,5-Dibromo-pentanoic acid benzyl-[1-(2-methyl-allyl)-2-oxo-cyclopentylmethyl]-amide