Technology Process of C14H15F4N3O
There total 8 articles about C14H15F4N3O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(l) iodide; sodium azide; sodium carbonate; N,N`-dimethylethylenediamine;
In
dimethyl sulfoxide;
at 110 ℃;
for 6h;
- Guidance literature:
-
C14H13BrF4N2O;
With
copper(l) iodide; sodium carbonate; N,N`-dimethylethylenediamine;
In
dimethyl sulfoxide;
at 110 ℃;
for 6h;
ammonium hydroxide;
In
water;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: hydrogenchloride / 1,4-dioxane; water / 0.5 h / 20 °C
2.1: sodium hydroxide / water; tetrahydrofuran / 15 °C / pH 10 - 11
2.2: pH 2
3.1: sodium hydrogencarbonate / N,N-dimethyl-formamide / 2 h / 8 °C
4.1: tetrabutylammonium triphenyldifluorosilicate / tetrahydrofuran / 2 h / 20 °C
5.1: diethylamino-sulfur trifluoride / dichloromethane / 1 h / 20 °C
6.1: tetraphosphorus decasulfide / tetrahydrofuran / 3 h / 20 - 70 °C
7.1: ammonium hydroxide; ammonia / water; quinoline / 1 h / 140 °C / Microwave irradiation
8.1: copper(l) iodide; N,N`-dimethylethylenediamine; sodium carbonate / dimethyl sulfoxide / 6 h / 110 °C
With
hydrogenchloride; ammonium hydroxide; copper(l) iodide; tetraphosphorus decasulfide; diethylamino-sulfur trifluoride; ammonia; sodium hydrogencarbonate; sodium carbonate; tetrabutylammonium triphenyldifluorosilicate; sodium hydroxide; N,N`-dimethylethylenediamine;
In
tetrahydrofuran; 1,4-dioxane; quinoline; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
