5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate

Base Information

• Chemical Name: 5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate
• CAS No.: 1279130-23-2
• Molecular Formula: C₁₆H₁₅NO₆S
• Molecular Weight: 349.364
• Mol file: 1279130-23-2.mol

Synonyms:5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate

Chemical Property of 5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate

There total 4 articles about 5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-(4-methylbenzenesulfonyl)-pyridine (51954-53-1) + acetic acid (64-19-7,77671-22-8) → 5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate (1279130-23-2)

Guidance literature:

With dipotassium peroxodisulfate; palladium diacetate; In 1,2-dichloro-ethane; at 80 ℃; for 18h; Inert atmosphere;

DOI:10.1002/adsc.201000941

Reference yield: 67.0%

2-(4-methylbenzenesulfonyl)-pyridine (51954-53-1) + acetic acid (64-19-7,77671-22-8) → 5-methyl-2-(2-pyridinylsulfonyl)phenyl acetate (1279130-22-1) + 5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate (1279130-23-2)

Guidance literature:

With dipotassium peroxodisulfate; palladium diacetate; In 1,2-dichloro-ethane; at 80 ℃; for 5h; Inert atmosphere;

DOI:10.1002/adsc.201000941

Reference yield:

2-(p-tolylthio)pyridine (51954-54-2) → 5-methyl-2-(2-pyridinylsulfonyl)-1,3-phenylene diacetate (1279130-23-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 °C

2: dipotassium peroxodisulfate; palladium diacetate / 1,2-dichloro-ethane / 18 h / 80 °C / Inert atmosphere

With dipotassium peroxodisulfate; palladium diacetate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 1,2-dichloro-ethane;

DOI:10.1002/adsc.201000941

upstream raw materials:

2-(p-tolylthio)pyridine

2-(4-methylbenzenesulfonyl)-pyridine

acetic acid

Downstream raw materials:

orcinol

1,3-dihydroxy-5-methyl disulfide