2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol

Base Information

• Chemical Name: 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol
• CAS No.: 192069-73-1
• Molecular Formula: C₁₉H₁₆Cl₂F₃NO₂
• Molecular Weight: 418.243

Synonyms:2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol

Chemical Property of 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol

There total 2 articles about 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-hydroxybenzotriazole hydrate [HOBT] + 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) + 3,4,5-trifluorobenzoic acid (121602-93-5,255875-61-7) + 3-(3,4-dichloro-phenyl)-3-(2-hydroxy-ethyl)-pyrrolidine (52423-89-9) → 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol (192069-73-1)

Guidance literature:

With hydrogenchloride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; In dichloromethane;

Reference yield:

1-hydroxy-benzotriazole hydrate (HOBT) + 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) + 3,4,5-trifluorobenzoic acid (121602-93-5,255875-61-7) + 3-(3,4-dichloro-phenyl)-3-(2-hydroxy-ethyl)-pyrrolidine (52423-89-9) → 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol (192069-73-1)

Guidance literature:

With hydrogenchloride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; In dichloromethane;

Reference yield:

2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol (192069-73-1) + methanesulfonyl chloride (124-63-0) → 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate (192069-74-2)

Guidance literature:

upstream raw materials:

3,4,5-trifluorobenzoic acid

3-(3,4-dichloro-phenyl)-3-(2-hydroxy-ethyl)-pyrrolidine

Downstream raw materials:

2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 192069-73-1 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trifluoro-benzoyl)-pyrrolidin-3-yl]-ethanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send