5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide

Base Information

• Chemical Name: 5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide
• CAS No.: 1040719-44-5
• Molecular Formula: C₂₀H₂₉N₅O₂
• Molecular Weight: 371.483

Synonyms:5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide

Chemical Property of 5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide

There total 4 articles about 5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

5-bromo-pentanoic acid [5-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-amide (1040724-60-4) + tert-butyl 1,4-diazepine-1-carboxylate (112275-50-0) → 5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide (1040719-44-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; sodium iodide; In 1-methyl-pyrrolidin-2-one; at 50 ℃; for 18h;

Reference yield:

1,4-Diazacycloheptane (505-66-8) + 5-bromo-pentanoic acid [5-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-amide (1040724-60-4) → 5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide (1040719-44-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; sodium iodide; In N,N-dimethyl-formamide; at 50 ℃; for 18h; Inert atmosphere;

DOI:10.1021/jm300247y

Reference yield:

5-amino-3-(4-methoxyphenyl)pyrazole (19541-95-8) → 5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide (1040719-44-5)

Guidance literature:

Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl acetamide / 2.5 h / -10 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine; sodium iodide / N,N-dimethyl-formamide / 18 h / 50 °C / Inert atmosphere

With N-ethyl-N,N-diisopropylamine; sodium iodide; In N,N-dimethyl acetamide; N,N-dimethyl-formamide;

DOI:10.1021/jm300247y

upstream raw materials:

5-bromo-pentanoic acid [5-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-amide

tert-butyl 1,4-diazepine-1-carboxylate

1,4-Diazacycloheptane

5-amino-3-(4-methoxyphenyl)pyrazole

Downstream raw materials:

SEN₁₅₉₂₄

C₂₄H₃₃N₅O₄

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1040719-44-5 5-[1,4]diazepan-1-yl-pentanoic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide

Send

Send

Metric Ton KG G Pound L ML

Send

Send