(E)-methyl 3-acetylcinnamate

Base Information

• Chemical Name: (E)-methyl 3-acetylcinnamate
• CAS No.: 1313813-62-5
• Molecular Formula: C₁₂H₁₂O₃
• Molecular Weight: 204.225
• Mol file: 1313813-62-5.mol

Synonyms:(E)-methyl 3-acetylcinnamate

Chemical Property of (E)-methyl 3-acetylcinnamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (E)-methyl 3-acetylcinnamate

There total 1 articles about (E)-methyl 3-acetylcinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-(3-Bromophenyl)ethanone (2142-63-4) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → (E)-methyl 3-acetylcinnamate (1313813-62-5)

Guidance literature:

With [CH₃PPh₃]₂[Pd₂Br₂Cl₄]; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 140 ℃; for 0.666667h;

DOI:10.1055/s-0032-1317963

Reference yield: 92.0%

(E)-methyl 3-acetylcinnamate (1313813-62-5) + ethanolamine (141-43-5) → (E)-N-(2-hydroxyethyl)-3-acetylcinnamamide (1494407-58-7)

Guidance literature:

With sodium carbonate; In methanol; at 80 ℃; for 2h; regioselective reaction;

DOI:10.1016/j.tetlet.2013.10.086

upstream raw materials:

1-(3-Bromophenyl)ethanone

acrylic acid methyl ester

Downstream raw materials:

(E)-N-(2-hydroxyethyl)-3-acetylcinnamamide