N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide

Base Information

Chemical Name:N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide
CAS No.:953066-26-7
Molecular Formula:C₂₃H₁₇ClFN₃O₂
Molecular Weight:421.858
Hs Code.:

Synonyms:N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide

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Chemical Property of N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide

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Technology Process of N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide

There total 2 articles about N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 155136-54-2
4-methylnicotinoyl chloride

: 953070-58-1
4-((3-chlorophenylamino)methyl)-8-fluoroquinolin-2(1H)-one

: 953066-26-7
N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide

Guidance literature:: 4-methylnicotinoyl chloride; 4-((3-chlorophenylamino)methyl)-8-fluoroquinolin-2(1H)-one; With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 25 ℃; for 14h; Inert atmosphere;

With propylamine; In 1-methyl-pyrrolidin-2-one; at 25 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/jm900173b