{(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene

Base Information

Chemical Name:{(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene
CAS No.:258846-78-5
Molecular Formula:C₂₇H₅₁N₃O₃Si₂
Molecular Weight:521.891
Hs Code.:

Synonyms:{(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene

Suppliers and Price of {(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene

There total 11 articles about {(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.4%

: 258846-76-3
Methanesulfonic acid (1S,2R,3R)-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-1-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-butyl ester

: 258846-78-5
{(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide;
DOI:10.1039/a907922j

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 258846-78-5
{(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene

Guidance literature:: Multi-step reaction with 11 steps

1: 70 percent / HMPA; LDA / -78 °C

2: 90 percent / imidazole / dimethylformamide

3: 86 percent / DIBAL-H / diethyl ether / -78 °C

4: (COCl)2; Et₃N; DMSO / CH₂Cl₂ / -65 - -55 °C

5: LiCl; i-Pr₂NEt / acetonitrile

6: 95 percent / DIBAL-H / diethyl ether / -78 °C

7: 76.5 percent / Ti(O-i-Pr)4; D-(-)-diisopropyl tartrate; t-BuOOH

8: 72.4 percent / diethyl ether / -20 - 0 °C

9: 84.4 percent / Et₃N; DMAP / CH₂Cl₂

10: 97.7 percent / pyridine

11: 76.4 percent / NaN₃ / dimethylformamide

With 1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; sodium azide; oxalyl dichloride; diisobutylaluminium hydride; D-(-)-diisopropyl tartrate; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; lithium chloride; lithium diisopropyl amide; In pyridine; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetonitrile; 1: Alkylation / 2: Substitution / 3: Reduction / 4: Oxidation / 5: Condensation / 6: Reduction / 7: Epoxidation / 8: Ring cleavage / 9: Substitution / 10: Mesylation / 11: Substitution;
DOI:10.1039/a907922j

Reference yield:

: 107441-54-3
(2R,3R)-methyl 2-[(benzyloxy)methyl]-3-hydroxybutyrate

: 258846-78-5
{(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene

Guidance literature:: Multi-step reaction with 10 steps

1: 90 percent / imidazole / dimethylformamide

2: 86 percent / DIBAL-H / diethyl ether / -78 °C

3: (COCl)2; Et₃N; DMSO / CH₂Cl₂ / -65 - -55 °C

4: LiCl; i-Pr₂NEt / acetonitrile

5: 95 percent / DIBAL-H / diethyl ether / -78 °C

6: 76.5 percent / Ti(O-i-Pr)4; D-(-)-diisopropyl tartrate; t-BuOOH

7: 72.4 percent / diethyl ether / -20 - 0 °C

8: 84.4 percent / Et₃N; DMAP / CH₂Cl₂

9: 97.7 percent / pyridine

10: 76.4 percent / NaN₃ / dimethylformamide

With 1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; dmap; sodium azide; oxalyl dichloride; diisobutylaluminium hydride; D-(-)-diisopropyl tartrate; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; lithium chloride; In pyridine; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetonitrile; 1: Substitution / 2: Reduction / 3: Oxidation / 4: Condensation / 5: Reduction / 6: Epoxidation / 7: Ring cleavage / 8: Substitution / 9: Mesylation / 10: Substitution;
DOI:10.1039/a907922j