107441-54-3

Upstream product

• 3587-60-8 Benzyloxymethyl chloride 
• 3976-69-0 Methyl (R)-3-hydroxybutyrate 

Downstream Products

• 258846-76-3 Methanesulfonic acid (1S,2R,3R)-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-1-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-butyl ester 
• 258846-78-5 {(2R,3S,4R)-3-Azido-5-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-pentyloxymethyl}-benzene 
• 258846-65-0 (2S,3S,4S,5R)-4-Benzyloxymethyl-1,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-methyl-hexan-3-ol 
• 258846-74-1 (2S,3S,4S,5R)-4-Benzyloxymethyl-5-(tert-butyl-dimethyl-silanyloxy)-2-methyl-hexane-1,3-diol 
• 258846-58-1 {(2R,3R)-3-[(1S,2R)-1-Benzyloxymethyl-2-(tert-butyl-dimethyl-silanyloxy)-propyl]-oxiranyl}-methanol 
• 258846-63-8 (E)-(4R,5R)-4-Benzyloxymethyl-5-(tert-butyl-dimethyl-silanyloxy)-hex-2-en-1-ol 
• 314031-43-1 (1R,2R)3-azido-2-[(benzyloxy)methyl]-(1-methylpropoxy)-tert-butyldimethylsilane 
• 258846-61-6 (2R,3R)-2-[(benzyloxy)methyl]-3-(tert-butyldimethylsiloxy)butan-1-ol 
• 107441-56-5 methyl (2R,3R)-2-[(benzyloxy)methyl]-3-(tert-butyldimethylsiloxy)butyrate 
• 107441-60-1 (9ξ)-benzyl (E)-9-<(benzyloxy)methyl>-10-O-(tert-butyldimethylsilyl)-6,7,9,11-tetradeoxy-2,3-O-isopropylidene-7-C-methyl-D-glycero-α-D-lyxo-undec-6-enofuranosido-5,5-diulose 
• 107441-68-9 (8ξ)-(2R,3S,5E,9R)-8-<(benzyloxy)methyl>-9-(tert-butyldimethylsiloxy)-1,3-dihydroxy-2,6-dimethyl-5-decene-4,7-dione dipivaloate 
• 107441-81-6 (4ξ,6ξ,8ξ)-6,9-anhydro-8-<(tert-butyldiphenylsiloxy)methyl>-2,5,8,10-tetradeoxy-1,3-O-isopropylidene-2-methyl-6-C-methyl-D-glycero-D-threo-decoulode pivaloate 
• 107441-80-5 (4ξ,6ξ,7ξ,8ξ)-6,9-anhydro-8-<(tert-butyldiphenylsiloxy)methyl>-2,5,8,10-tetradeoxy-1,3-O-isopropylidene-2-methyl-6-C-methyl-D-glycero-D-threo-decitol 4-pivaloate 
• 107441-76-9 (4ξ,6ξ,7ξ,8ξ)-6,9-anhydro-7-O-benzyl-1,3-O-benzylidene-8-<(benzyloxy)methyl>-2,5,8,10-tetradeoxy-2-methyl-6-C-methyl-D-glycero-D-threo-4,7-decitol pivaloate 

Relevant academic research and scientific papers

A new diastereoselective synthesis of a 1β-methylcarbapenem intermediate

A 1β-methylcarbapenem key intermediate is synthesized from methyl (R)- 3-hydroxybutyrate via the diastereoselective alkylation and regioselective cuprate ring opening of a chiral epoxide which is readily prepared from Sharpless asymmetric epoxidation of the corresponding allylic alcohol.

ARTIFICIAL NUCLEIC ACIDS

Artificial nucleosides including 2-methyl-nucleobase-substituted butane-1,3-diol nucleosides are disclosed. Four different stereoisomers of such nucleosides are possible. Oligonucleotides made up of the artificial nucleosides form homoduplexes of greater stability than DNA duplexes and have a reduced ability to hybridize to DNA or RNA.

3-Acyltetramic Acid Antibiotics. 3. An Approach to the Synthesis of Bu-2313

An approach to the synthesis of the bicyclononane portion of the 3-acyltetramic acid antibiotic Bu-2313 is presented.The highly unstable α-keto aldehyde obtained by Swern oxidation of the diol 23 was allowed to condense with the unreactive α-keto phosphor