(3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate

Base Information

Chemical Name:(3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate
CAS No.:1589556-08-0
Molecular Formula:C₂HF₃O₂*C₁₆H₂₀N₂O₃
Molecular Weight:402.37
Hs Code.:

Synonyms:(3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate

Suppliers and Price of (3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate

There total 2 articles about (3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1589556-07-9
tert-butyl ((3R,11R,E)-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl)carbamate

: 76-05-1
trifluoroacetic acid

: 1589556-08-0
(3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate

Guidance literature:: With triethylsilane; In dichloromethane; at 20 ℃; for 4h;

Reference yield:

: 1589558-50-8
tert-butyl ((4R,8S)-5-oxo-8-(pent-4-enamido)-8-phenyloct-1-en-4-yl)carbamate

: 1589556-08-0
(3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; 3-carboxy-2-mercaptopyridine / dichloromethane / 3 h / 20 °C

2: triethylsilane / dichloromethane / 4 h / 20 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; triethylsilane; 3-carboxy-2-mercaptopyridine; In dichloromethane;

Reference yield: 99.0%

: 1589556-08-0
(3R,11R,E)-11-amino-3-phenyl-1-oxa-4-azacyclododec-8 ene-5,12-dione trifluoroacetate

: 1589555-16-7
(3R,11R,E)-11-azido-3-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione

Guidance literature:: With sodium azide; copper(ll) sulfate pentahydrate; potassium carbonate; trifluoromethanesulfonic acid anhydride; In methanol; dichloromethane; water; at 20 ℃; for 14h; Cooling with ice;