1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde)

Base Information

• Chemical Name: 1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde)
• CAS No.: 155791-74-5
• Molecular Formula: C₁₈H₂₆N₄O₂
• Molecular Weight: 330.43
• Mol file: 155791-74-5.mol

Synonyms:1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde)

Chemical Property of 1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde)

There total 1 articles about 1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1,4-bis(bromomethyl)benzene (623-24-5) + piperazine-1-carbaldehyde (7755-92-2) → 1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde) (155791-74-5)

Guidance literature:

With potassium carbonate; In methanol; Heating;

DOI:10.1021/jm00034a004

Reference yield: 78.0%

1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde) (155791-74-5) → α,α′-p-xylylenebis(1-piperazine) (25741-48-4)

Guidance literature:

With potassium hydroxide; In ethanol; for 24h; Heating;

DOI:10.1016/j.tet.2008.01.105

Reference yield: 16.0%

1,1'-[1,4-phenylenebis(methylene)]bis(4-piperazinecarbaldehyde) (155791-74-5) → α,α′-p-xylylenebis(1-piperazine) (25741-48-4) + 1,4-Bis-(4-piperazin-1-ylmethyl-benzyl)-piperazine

Guidance literature:

With hydrogenchloride; In ethanol;

DOI:10.1021/jm00034a004

upstream raw materials:

1,4-bis(bromomethyl)benzene

piperazine-1-carbaldehyde

Downstream raw materials:

α,α′-p-xylylenebis(1-piperazine)