10,11-Dihydrodibenzo(b,f)thiepin-10-carboxamide

Base Information

Chemical Name:10,11-Dihydrodibenzo(b,f)thiepin-10-carboxamide
CAS No.:87033-42-9
Molecular Formula:C₁₅H₁₃NOS
Molecular Weight:255.34
Hs Code.:
DSSTox Substance ID:DTXSID101007268

Synonyms:BRN 4452597;10,11-Dihydrodibenzo(b,f)thiepin-10-carboxamide;87033-42-9;Dibenzo(b,f)thiepin-10-carboxamide, 10,11-dihydro-;Oprea1_360177;DTXSID101007268;LS-61370;10,11-Dihydrodibenzo[b,f]thiepine-10-carboximidic acid

Suppliers and Price of 10,11-Dihydrodibenzo(b,f)thiepin-10-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 10,11-Dihydrodibenzo(b,f)thiepin-10-carboxamide

Chemical Property:

Vapor Pressure:3.46E-08mmHg at 25°C
Boiling Point:447.1°Cat760mmHg
Flash Point:224.2°C
Density:1.265g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:255.07178521
Heavy Atom Count:18
Complexity:320

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C2=CC=CC=C2SC3=CC=CC=C31)C(=O)N

Technology Process of 10,11-Dihydrodibenzo(b,f)thiepin-10-carboxamide

There total 9 articles about 10,11-Dihydrodibenzo(b,f)thiepin-10-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

: 36943-49-4
dibenzothiepin-10 carbonitrile

: 87033-42-9
10,11-dihydrodibenzothiepin-10-carboxamide

: 87033-40-7
10,11-dihydrodibenzothiepin-10-carbonitrile

Guidance literature:: With sodium hydroxide; sodium tetrahydroborate; In ethanol; for 11h; Heating;
DOI:10.1135/cccc19831187

Reference yield:

: 4521-31-7
o-hydroxymethyl thiophenol

: 87033-42-9
10,11-dihydrodibenzothiepin-10-carboxamide

Guidance literature:: Multi-step reaction with 5 steps

1: 65 percent / K₂CO₃, Cu / dimethylformamide / 14 h / Heating

2: 92 percent / SOCl₂ / benzene / 2 h / Heating

3: 25 percent / powdered KOH / dimethylsulfoxide / 2 h / 25 - 30 °C

4: 1.) ZnI₂, 2.) POCl₃ / 1.) benzene, R_.T_. 8 h, 2.) pyridine, reflux 6 h.

5: 38 percent / NaBH₄, 20 percent NaOH / ethanol / 11 h / Heating

With potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; thionyl chloride; copper; potassium carbonate; zinc(II) iodide; trichlorophosphate; In ethanol; dimethyl sulfoxide; N,N-dimethyl-formamide; benzene;
DOI:10.1135/cccc19831187

Reference yield:

: 63744-05-8
2-(2-hydroxymethylphenylthio)benzaldehyde

: 87033-42-9
10,11-dihydrodibenzothiepin-10-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

2: 38 percent / NaBH₄, 20 percent NaOH / ethanol / 11 h / Heating

With sodium hydroxide; sodium tetrahydroborate; In ethanol;
DOI:10.1135/cccc19831187