S-[2-(dipropan-2-ylamino)ethyl] 4-fluorobenzenesulfonothioate hydrochloride (1:1)

Base Information

• Chemical Name: S-[2-(dipropan-2-ylamino)ethyl] 4-fluorobenzenesulfonothioate hydrochloride (1:1)
• CAS No.: 139131-36-5
• Molecular Formula: C14H23ClFNO2S2
• Molecular Weight: 355.9193
• Mol file: 139131-36-5.mol

Synonyms:

Chemical Property of S-[2-(dipropan-2-ylamino)ethyl] 4-fluorobenzenesulfonothioate hydrochloride (1:1)

Chemical Property:

• Vapor Pressure: 1.17E-06mmHg at 25°C
• Boiling Point: 401.5°Cat760mmHg
• Flash Point: 196.6°C
• Density: g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-[2-(dipropan-2-ylamino)ethyl] 4-fluorobenzenesulfonothioate hydrochloride (1:1)

There total 3 articles about S-[2-(dipropan-2-ylamino)ethyl] 4-fluorobenzenesulfonothioate hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

β-(Diisopropylamino)ethyl p-fluorobenzenethiosulfonate (139131-31-0) → β-(Diisopropylamino)ethyl p-fluorobenzenethiosulfonate hydrochloride (139131-36-5)

Guidance literature:

With hydrogenchloride; at 25 ℃; for 48h;

DOI:10.1021/jo00035a013

Reference yield:

4-Fluorobenzenesulfonyl chloride (349-88-2) → β-(Diisopropylamino)ethyl p-fluorobenzenethiosulfonate hydrochloride (139131-36-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 60 percent / H₂S, aq. KOH / 3 h / 20 - 25 °C

2: 64 percent / tBuOK, Adogen-464 / various solvent(s) / 15 h / Ambient temperature

3: 83 percent / 5percent aq. HCl / 48 h / 25 °C

With hydrogenchloride; potassium hydroxide; Adogen-464; hydrogen sulfide; potassium tert-butylate; In various solvent(s);

DOI:10.1021/jo00035a013

Reference yield:

Potassium p-Fluorobenzenethiosulfonic Acid (139131-32-1) → β-(Diisopropylamino)ethyl p-fluorobenzenethiosulfonate hydrochloride (139131-36-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / tBuOK, Adogen-464 / various solvent(s) / 15 h / Ambient temperature

2: 83 percent / 5percent aq. HCl / 48 h / 25 °C

With hydrogenchloride; Adogen-464; potassium tert-butylate; In various solvent(s);

DOI:10.1021/jo00035a013

upstream raw materials:

β-(Diisopropylamino)ethyl p-fluorobenzenethiosulfonate

4-Fluorobenzenesulfonyl chloride

Potassium p-Fluorobenzenethiosulfonic Acid

Refernces