4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide

Base Information

Chemical Name:4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide
CAS No.:1390617-35-2
Molecular Formula:C₂₄H₂₉FN₄O₇S
Molecular Weight:536.581
Hs Code.:

Synonyms:4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide

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Chemical Property of 4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide

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Technology Process of 4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide

There total 5 articles about 4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 71675-87-1
2-methoxy-4-amino-5-ethylsulphonyl benzoic acid

: 168828-90-8
(S)-N-[[3-[3-fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]amine

: 1390617-35-2
4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide

Guidance literature:: 2-methoxy-4-amino-5-ethylsulphonyl benzoic acid; With chloroformic acid ethyl ester; triethylamine; In dichloromethane; at 0 - 20 ℃; for 0.5h;

(S)-N-[[3-[3-fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]amine; In dichloromethane; at 0 - 20 ℃; for 4h;

Reference yield:

: 93246-53-8
3-fluoro-4-(morpholinyl)aniline

: 1390617-35-2
4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: N,N-dimethyl-formamide

2.1: dichloromethane

3.1: hydrazine hydrate / methanol

4.1: chloroformic acid ethyl ester; triethylamine / dichloromethane / 0.5 h / 0 - 20 °C

4.2: 4 h / 0 - 20 °C

With chloroformic acid ethyl ester; hydrazine hydrate; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 168828-89-5,947736-16-5
2-({(5S)-2-oxo-3-[(4-morpholino-3-fluorophenyl)]-4,5-dihydro-1,3-oxazole-5-yl}methyl)-isoindole-1,3-dione

: 1390617-35-2
4-amino-5-(ethylsulfonyl)-N-(S)-[[3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl]methyl]-2-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine hydrate / methanol

2.1: chloroformic acid ethyl ester; triethylamine / dichloromethane / 0.5 h / 0 - 20 °C

2.2: 4 h / 0 - 20 °C

With chloroformic acid ethyl ester; hydrazine hydrate; triethylamine; In methanol; dichloromethane;