methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate

Base Information

Chemical Name:methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate
CAS No.:142566-72-1
Molecular Formula:C₂₅H₃₄O₃Si
Molecular Weight:410.629
Hs Code.:

Synonyms:methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate

Suppliers and Price of methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate

There total 13 articles about methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3846-07-9
dimethyl 1,4,4a,5,8,8a-hexahydronaphhtalene-cis-4a,8a-dicarboxylate

: 142566-72-1
methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate

Guidance literature:: Multi-step reaction with 8 steps

1: 100 percent / Na-K / diethyl ether / 4 h / Ambient temperature

2: 96 percent / methanol / 20 h / Ambient temperature

3: 96 percent / Et₃N / CH₂Cl₂ / 3 h / 0 °C

4: 96 percent / aq. LiOH / tetrahydrofuran / 24 h / Ambient temperature

5: 95 percent / aq. KI, I₂, aq. NaHCO₃ / 24 h

6: 97 percent / DBU / benzene / 24 h / Ambient temperature

7: 1.) BuLi, 2.) CuBr*Me₂S

8: K₂CO₃ / acetonitrile / 3 h / Ambient temperature

With lithium hydroxide; n-butyllithium; potassium Sodium; copper(I) bromide dimethylsulfide complex; iodine; sodium hydrogencarbonate; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; potassium iodide; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; acetonitrile; benzene;
DOI:10.1021/ja00102a020

Reference yield:

: 3642-04-4
1,4,4a,5,8,8a-hexahydronaphthalene-cis-4a,8a-dicarboxylic acid

: 142566-72-1
methyl 4-(3-((tert-butyldimethylsilyl)oxy)phenyl)<4.4.1>propella-2,8-diene-11-carboxylate

Guidance literature:: Multi-step reaction with 9 steps

1: 100 percent / K₂CO₃ / acetonitrile / 3 h

2: 100 percent / Na-K / diethyl ether / 4 h / Ambient temperature

3: 96 percent / methanol / 20 h / Ambient temperature

4: 96 percent / Et₃N / CH₂Cl₂ / 3 h / 0 °C

5: 96 percent / aq. LiOH / tetrahydrofuran / 24 h / Ambient temperature

6: 95 percent / aq. KI, I₂, aq. NaHCO₃ / 24 h

7: 97 percent / DBU / benzene / 24 h / Ambient temperature

8: 1.) BuLi, 2.) CuBr*Me₂S

9: K₂CO₃ / acetonitrile / 3 h / Ambient temperature

With lithium hydroxide; n-butyllithium; potassium Sodium; copper(I) bromide dimethylsulfide complex; iodine; sodium hydrogencarbonate; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; potassium iodide; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; acetonitrile; benzene;
DOI:10.1021/ja00102a020