(3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite

Base Information

Chemical Name:(3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite
CAS No.:1315454-26-2
Molecular Formula:C₄₉H₆₉N₂O₅P
Molecular Weight:797.071
Hs Code.:

Synonyms:(3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite

Suppliers and Price of (3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite

There total 3 articles about (3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 1315454-21-7
2,2'-(1-hydroxymethyl-2-phenylethylidene)bis[(4S)-4-isopropyl-4,5-dihydro-oxazole]

: 71941-98-5
3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl phosphorochloridite

: 1315454-26-2
(3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite

Guidance literature:: With dmap; In toluene; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2011.05.079

Reference yield:

: 100-39-0
benzyl bromide

: 1315454-26-2
(3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium tert-butylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

1.2: 4 h / Inert atmosphere; Reflux

2.1: water; triethylamine / tetrahydrofuran; 1,4-dioxane; dichloromethane / 72 h / 20 °C / Inert atmosphere

3.1: dmap / toluene / 0 - 20 °C / Inert atmosphere

With dmap; potassium tert-butylate; water; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane; toluene;
DOI:10.1016/j.tet.2011.05.079

Reference yield:

: 131833-90-4,152754-11-5
2,2'-methylenebis[(4S)-4-isopropyl-4,5-dihydro-oxazole]

: 1315454-26-2
(3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)-{2,2-bis[(4S)-4-isopropyl-4,5-dihydro-oxazol-2-yl]-3-phenylpropyl}-phosphite

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium tert-butylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

1.2: 4 h / Inert atmosphere; Reflux

2.1: water; triethylamine / tetrahydrofuran; 1,4-dioxane; dichloromethane / 72 h / 20 °C / Inert atmosphere

3.1: dmap / toluene / 0 - 20 °C / Inert atmosphere

With dmap; potassium tert-butylate; water; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane; toluene;
DOI:10.1016/j.tet.2011.05.079